Bahemuka M
Department of Medicine, King Saud University, Riyadh, Saudi Arabia.
Brain. 1988 Jun;111 ( Pt 3):737-55. doi: 10.1093/brain/111.3.737.
International and interregional comparisons of average annual age-adjusted incidence rates for primary tumours of the nervous system showed marked variations. The highest rates were observed in those areas having high socioeconomic levels. In communities with multiple racial groups the highest rates were in Caucasians. Migrant populations retained rates close to those found in the country of origin. The majority of populations showed modest increases only while about one-third showed a decrease in the incidence rates during a period of approximately 15 years. Overall, there was a male excess. It is suggested that differences in medical practices (including availability of specialist expertise), diagnostic facilities and individual registry practices account for some of the variations observed. However, the possible aetiological roles of genetic, racial, hormonal and environmental factors need to be evaluated to explain the consistently higher incidence rates in Caucasians and in males of all races.
对神经系统原发性肿瘤的年均年龄调整发病率进行的国际和区域间比较显示出显著差异。在社会经济水平较高的地区观察到最高发病率。在有多个种族群体的社区中，白种人的发病率最高。移民群体的发病率与原籍国相近。在大约15年的时间里，大多数人群的发病率仅略有上升，而约三分之一的人群发病率呈下降趋势。总体而言，男性发病率更高。有人认为，医疗实践（包括专科专业知识的可及性）、诊断设施和个体登记实践方面的差异是观察到的一些差异的原因。然而，需要评估遗传、种族、激素和环境因素可能的病因学作用，以解释白种人和所有种族男性中持续较高的发病率。
