Bahemuka M, Massey E W, Schoenberg B S
Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Int J Epidemiol. 1988 Mar;17(1):33-8. doi: 10.1093/ije/17.1.33.
International comparisons of average annual age-adjusted mortality rates for primary tumours of the nervous system for 1951 through 1958 and 1967 through 1973 showed marked geographical variation for both study periods. For the majority of countries, the mortality rates increased by at least 40% in the in the intervening 15-year period, while in 20% of the countries the rates increased by over 100%. The percentage increases varied from 12.2 to 345.5. The improvement in the diagnosis of these tumours, particularly among elderly individuals (who have the highest age-specific incidence rates for these neoplasms), presumably accounts for most of this change. However, it is possible that the increase may not be fully accounted for by these factors alone. It is therefore suggested that further epidemiological studies are undertaken to determine more accurately the causes and implications of this worldwide increase in mortality rates from primary tumours of the nervous system.
1951年至1958年以及1967年至1973年期间，对神经系统原发性肿瘤年龄调整后的平均年死亡率进行的国际比较显示，在这两个研究期间均存在显著的地理差异。对于大多数国家而言，在这中间的15年期间，死亡率至少上升了40%，而在20%的国家中，死亡率上升超过了100%。上升百分比从12.2到345.5不等。这些肿瘤诊断水平的提高，尤其是在老年人（这些肿瘤年龄别发病率最高的人群）中的诊断水平提高，可能是造成这种变化的主要原因。然而，这种增加可能不完全是由这些因素造成的。因此，建议开展进一步的流行病学研究，以更准确地确定全球范围内神经系统原发性肿瘤死亡率上升的原因及其影响。
