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一项在土耳其南部进行的流行病学研究,旨在明确近期感染性心内膜炎的临床特征和结局。

An epidemiological study to define the recent clinical characteristics and outcomes of infective endocarditis in southern Turkey.

机构信息

Department of Cardiology, Baskent University School of Medicine, Dr Turgut Noyan Application and Research Center, Adana, Turkey. Email:

Department of Cardiology, Baskent University School of Medicine, Dr Turgut Noyan Application and Research Center, Adana, Turkey.

出版信息

Cardiovasc J Afr. 2021;32(4):188-192. doi: 10.5830/CVJA-2021-009. Epub 2021 Apr 7.

Abstract

INTRODUCTION

The aim of this study was to characterise the recent features of patients with infective endocarditis (IE) at one referral centre in southern Turkey, in order to be able to identify the high-risk subgroup and revise preventative measures and management strategies.

METHODS

Medical records of patients 18 years and older, who had been diagnosed with IE according to the Duke criteria between January 2009 and October 2019, were retrospectively evaluated in a referral general hospital.

RESULTS

The total of 139 IE cases comprised 59.7% males and 40.3% females, with a mean age of 55 ± 16 years. The most encountered symptom was fever (55.4%) and the mitral valve (54%) was the most frequently involved. The most common causative micro-organisms were coagulase-negative staphylococci (30.2%). The in-hospital mortality rate was 30.2%, with congestive heart failure, chronic renal disease and chronic dialysis found to be significantly associated with in-hospital mortality.

CONCLUSIONS

The study results demonstrate the recent epidemiological features of IE in southern Turkey that are important for clinicians to manage diagnostic and therapeutic processes successfully. Older age, the predominance of staphylococci and higher surgery rates are consistent with the changing trends of IE in some parts the world.

摘要

介绍

本研究旨在描述土耳其南部一家转诊中心近期感染性心内膜炎(IE)患者的特征,以便能够确定高危亚组,并修订预防措施和管理策略。

方法

在一家转诊综合医院,对 2009 年 1 月至 2019 年 10 月期间根据 Duke 标准诊断为 IE 的 18 岁及以上患者的病历进行回顾性评估。

结果

共 139 例 IE 病例中,男性占 59.7%,女性占 40.3%,平均年龄为 55 ± 16 岁。最常见的症状是发热(55.4%),最常受累的瓣膜是二尖瓣(54%)。最常见的病原体是凝固酶阴性葡萄球菌(30.2%)。住院死亡率为 30.2%,充血性心力衰竭、慢性肾脏病和慢性透析与住院死亡率显著相关。

结论

本研究结果表明,土耳其南部 IE 的近期流行病学特征对临床医生成功管理诊断和治疗过程非常重要。年龄较大、葡萄球菌为主和更高的手术率与世界某些地区 IE 的变化趋势一致。

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Infective endocarditis in Western Norway: a 20-year retrospective survey.挪威西部的感染性心内膜炎:一项 20 年回顾性调查。
Infect Dis (Lond). 2018 Oct;50(10):757-763. doi: 10.1080/23744235.2018.1482419. Epub 2018 Jun 19.
4
Early surgery for acute-onset infective endocarditis.急性感染性心内膜炎的早期手术治疗。
Eur J Cardiothorac Surg. 2018 Dec 1;54(6):1060-1066. doi: 10.1093/ejcts/ezy208.
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Infective endocarditis.感染性心内膜炎。
Lancet. 2016 Feb 27;387(10021):882-93. doi: 10.1016/S0140-6736(15)00067-7. Epub 2015 Sep 1.

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