Department of Surgery, LaBahn Pancreatic Cancer Program, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
J Surg Oncol. 2021 May;123(6):1405-1413. doi: 10.1002/jso.26395.
Treatment of localized pancreatic cancer has also evolved to prioritize preoperative (neoadjuvant) multimodality therapy over a surgery-first approach. Given the complexities of pancreatic cancer staging and the challenge of delivering multiple treatment modalities (chemotherapy, radiation therapy, and surgery), an experienced and highly integrated multidisciplinary team is necessary to achieve the best outcomes. In this review, we will discuss our institutional experience with neoadjuvant therapy, guiding principles for treatment, and outline the landscape for future investigations.
局部胰腺癌的治疗方法也已经发展为优先采用术前（新辅助）多模式治疗，而不是首选手术治疗。鉴于胰腺癌分期的复杂性和提供多种治疗方式（化疗、放疗和手术）的挑战，需要一个经验丰富且高度整合的多学科团队来实现最佳治疗效果。在这篇综述中，我们将讨论我们机构在新辅助治疗方面的经验、治疗指导原则，并概述未来研究的前景。
