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儿童 COVID-19 的放射学表现。

Pediatric radiologic manifestations of COVID-19.

机构信息

Department of Radiology, University of Washington and Seattle Children's Hospital, 4800 Sand Point Way NE, Seattle, WA 98105, United States of America.

Department of Radiology, University of Washington and Seattle Children's Hospital, 4800 Sand Point Way NE, Seattle, WA 98105, United States of America.

出版信息

Clin Imaging. 2021 Jul;75:165-170. doi: 10.1016/j.clinimag.2021.03.032. Epub 2021 Mar 30.

Abstract

PURPOSE

While full description of pediatric COVID-19 manifestations is evolving, children appear to present less frequently, and often display a less severe disease phenotype. There is correspondingly less data regarding pediatric radiologic findings. To describe the imaging findings of pediatric COVID-19, we evaluated the radiologic imaging of the initial patient cohort identified at our institution.

METHODS

In this IRB approved study, all patients at our institution aged 0-21 with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) based on PCR or immunoglobulin testing were identified. Imaging was reviewed by the co-authors and presence of abnormalities determined by consensus. Pre-existing comorbidities and alternative diagnoses were recorded. Rates of each finding were calculated. Findings were compared to published data following review of the available literature.

RESULTS

Out of 130 Covid-19 positive patients, 24 patients underwent imaging, including 21 chest radiographs and 4 chest CT scans. Chest x-rays were normal in 33%. Patchy or streaky opacities were the most common radiographic abnormality, each seen in 38% of patients. CT findings included ill-defined or geographic ground glass opacities, dense opacities, septal thickening and crazy paving, and small pleural effusions. Results are similar to those reported in adults. Multiple COVID-19 positive children presented for symptoms due to an additional acute illness, including appendicitis and urinary infection.

CONCLUSIONS

Radiologic findings of COVID-19 in pediatric patients range from normal to severe ARDS type appearance. During this ongoing pandemic, these radiographic signs can be useful for the evaluation of disease status and guiding care, particularly in those with comorbidities.

PRECIS

Radiologic findings of COVID-19 in pediatric patients are similar to those seen in adults, and may range from normal to severe ARDS type appearance.

摘要

目的

虽然儿童 COVID-19 表现的全面描述仍在不断发展,但儿童患者的发病率似乎较低,且疾病表型通常较轻。因此,有关儿科放射学发现的数据较少。为了描述儿科 COVID-19 的影像学表现,我们评估了我院最初确定的患者队列的影像学检查结果。

方法

在这项经过机构审查委员会批准的研究中,我们确定了我院所有年龄在 0-21 岁之间、基于 PCR 或免疫球蛋白检测为严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)阳性的患者。由两位作者共同对影像学结果进行评估,并通过共识确定是否存在异常。记录了患者的既往合并症和其他诊断。计算了每种表现的发生率。在对现有文献进行综述后,将我们的发现与已发表的数据进行了比较。

结果

在 130 例 COVID-19 阳性患者中,有 24 例行影像学检查,包括 21 例胸部 X 线片和 4 例胸部 CT 扫描。33%的胸部 X 线片正常。斑片状或条纹状混浊是最常见的放射学异常,分别见于 38%的患者。CT 发现包括边界不清或局灶性磨玻璃影、致密影、间隔增厚和铺路石征以及少量胸腔积液。结果与成人报道的结果相似。多名 COVID-19 阳性儿童因其他急性疾病就诊,包括阑尾炎和尿路感染。

结论

儿科 COVID-19 患者的放射学表现从正常到严重的 ARDS 类型表现不等。在当前的大流行期间,这些放射学征象可用于评估疾病状态和指导治疗,尤其是对有合并症的患者。

重点

儿科 COVID-19 患者的放射学表现与成人相似,可能从正常到严重的 ARDS 类型表现不等。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d75e/8008832/d7102d7d0635/gr1_lrg.jpg

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