前列腺癌睾丸转移：是否被低估了？病例报告及文献分析。
Prostate cancer testicular metastasis: Are they underestimated? Case report and analysis of the literature.
作者信息
Smelzo Salvatore, Mantica Guglielmo, Lucianò Roberta, Tenace Nazario Pio, De Marchi Davide, Pini Giovannalberto, Passaretti Giovanni, Losa Andrea, Gaboardi Franco
机构信息
Department of Urology, San Raffaele Turro Hospital, San Raffaele University, Milan, Italy.
Department of Urology, Policlinico San Martino Hospital, University of Genova, Genova, Italy.
出版信息
Urologia. 2022 Nov;89(4):645-647. doi: 10.1177/03915603211009118. Epub 2021 Apr 8.
INTRODUCTION
We aim to present a rare case of a patient who developed a late testicular metastasis of PCa after radical prostatectomy.
CASE DESCRIPTION
A 78 years old man presenting for left testicular swelling slowly increasing of size over the last 2 months. He underwent a retropubic radical prostatectomy and extended bilateral lymphadenectomy in 2007 for prostatic adenocarcinoma. At the time of the presentation the last PSA was 0.91 ng/mL. The patient underwent a standard left orchifunicolectomy in April 2019 without intra- or perioperative complications. The pathological analysis showed a testicular metastasis of acinar adenocarcinoma.
CONCLUSIONS
In conclusion, testicular metastasis from PCa are uncommon conditions. PSA evaluation and physical examination of all sites of metastasis and accurate evaluation of all signs/symptoms during the clinical visit remains crucial to the diagnosis of recurrence.
引言
我们旨在介绍一例罕见病例，该患者在根治性前列腺切除术后发生了前列腺癌的晚期睾丸转移。
病例描述
一名78岁男性，因左侧睾丸肿大就诊，在过去2个月中，睾丸大小逐渐增加。他于2007年因前列腺腺癌接受了耻骨后根治性前列腺切除术及扩大双侧淋巴结清扫术。就诊时，末次前列腺特异抗原（PSA）为0.91 ng/mL。该患者于2019年4月接受了标准的左侧睾丸切除术，术中及围手术期均无并发症。病理分析显示为腺泡腺癌的睾丸转移。
结论
总之，前列腺癌的睾丸转移是罕见情况。PSA评估、对所有转移部位的体格检查以及临床就诊时对所有体征/症状的准确评估对于复发的诊断仍然至关重要。
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