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一例前列腺癌转移至肾脏和胃部的非典型转移途径病例报告。

A case report on the atypical metastatic pathway of prostate cancer to the kidney and stomach.

作者信息

Hsu Jhe-Yuan, Lin Yi-Sheng, Huang Li-Hua, Wen Wei-Chun, Gao Hong-Wei, Hsu Chao-Yu, Ou Yen-Chuan, Tung Min-Che

机构信息

Division of Urology, Department of Surgery, Tungs' Taichung MetroHarbor Hospital, Taichung, Taiwan.

Department of Pathology, Tungs' Taichung MetroHarbor Hospital, Taichung, Taiwan.

出版信息

Urol Case Rep. 2024 Aug 3;56:102816. doi: 10.1016/j.eucr.2024.102816. eCollection 2024 Sep.

DOI:10.1016/j.eucr.2024.102816
PMID:39224665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11366899/
Abstract

Prostate cancer rarely metastasizes to the stomach and kidneys. We report a 73-year-old male with such spread, highlighting significant clinical challenges. Initially diagnosed via biopsy and imaging, he received hormone therapy and cytoreductive radical prostatectomy. Despite initial management, the cancer progressed to metastatic castration-resistant prostate cancer, with gastric and renal metastases confirmed by imaging and biopsy. This case emphasizes the need for awareness of rare metastatic sites, comprehensive diagnostic evaluations, and further research into these atypical metastases to improve patient outcomes and develop better treatment strategies for managing advanced prostate cancer effectively.

摘要

前列腺癌很少转移至胃和肾脏。我们报告了一名73岁有此类转移的男性患者,突出了显著的临床挑战。最初通过活检和影像学检查确诊,他接受了激素治疗和减瘤性根治性前列腺切除术。尽管进行了初始治疗,癌症仍进展为转移性去势抵抗性前列腺癌,影像学和活检证实有胃和肾转移。该病例强调了需要认识到罕见的转移部位、进行全面的诊断评估,并对这些非典型转移进行进一步研究,以改善患者预后并制定更好的治疗策略来有效管理晚期前列腺癌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/754e/11366899/6b6152599c48/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/754e/11366899/945fa18cb718/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/754e/11366899/7801f081e09a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/754e/11366899/6b6152599c48/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/754e/11366899/945fa18cb718/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/754e/11366899/7801f081e09a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/754e/11366899/6b6152599c48/gr3.jpg

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本文引用的文献

1
Prostate Cancer Metastasis to Stomach: A Case Report and Review of Literature.前列腺癌转移至胃:病例报告及文献复习。
Curr Oncol. 2023 Mar 30;30(4):3901-3914. doi: 10.3390/curroncol30040295.
2
Prostate cancer testicular metastasis: Are they underestimated? Case report and analysis of the literature.前列腺癌睾丸转移:是否被低估了?病例报告及文献分析。
Urologia. 2022 Nov;89(4):645-647. doi: 10.1177/03915603211009118. Epub 2021 Apr 8.
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Metastases to the Kidney: An Analysis of 35 Cases and a Review of Literature.肾转移瘤:35例病例分析及文献复习
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Metastatic Prostate Cancer to the Renal Pelvis and Proximal Ureter: A Case Report and Review of the Literature.转移性前列腺癌侵犯肾盂及近端输尿管:一例报告并文献复习
Cancer Stud Ther. 2019 Sep;4(4). Epub 2019 Aug 11.
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Prostate cancer solitary metastasis to anal canal: case report and review of literature.前列腺癌单一转移至肛管:病例报告及文献复习。
BMC Cancer. 2019 Apr 23;19(1):374. doi: 10.1186/s12885-019-5573-9.
6
Tumor necrosis factor-α induces prostate cancer cell migration in lymphatic metastasis through CCR7 upregulation.肿瘤坏死因子-α通过上调 CCR7 诱导前列腺癌细胞淋巴转移。
Cancer Sci. 2018 May;109(5):1524-1531. doi: 10.1111/cas.13586. Epub 2018 Apr 29.
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Renal and retroperitoneal metastasis from prostate adenocarcinoma: a case report.前列腺腺癌的肾及腹膜后转移:一例报告
World J Surg Oncol. 2016 Mar 9;14:74. doi: 10.1186/s12957-016-0834-4.
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Prevalence of incidental prostate cancer: A systematic review of autopsy studies.偶发性前列腺癌的患病率:尸检研究的系统评价
Int J Cancer. 2015 Oct 1;137(7):1749-57. doi: 10.1002/ijc.29538. Epub 2015 Apr 21.
9
Synchronous metastasis of prostate adenocarcinoma to the stomach and colon: a case report.前列腺腺癌同步转移至胃和结肠:一例报告
N Am J Med Sci. 2014 Mar;6(3):152-4. doi: 10.4103/1947-2714.128478.
10
Prostate cancer metastasis to the stomach.前列腺癌转移至胃。
Korean J Urol. 2010 Jun;51(6):431-3. doi: 10.4111/kju.2010.51.6.431. Epub 2010 Jun 21.