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一名患有前列腺癌并伴有睾丸转移的年轻患者。

A young patient with prostatic carcinoma with testicular metastasis.

作者信息

Balagobi B, Gobishangar S, Sarma S T, Brammah R T, Jenil A

机构信息

University Surgical Unit, Teaching Hospital Jaffna, Sri Lanka.

University Surgical Unit, Teaching Hospital Jaffna, Sri Lanka.

出版信息

Int J Surg Case Rep. 2022 Oct;99:107653. doi: 10.1016/j.ijscr.2022.107653. Epub 2022 Sep 13.

DOI:10.1016/j.ijscr.2022.107653
PMID:36115121
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9568776/
Abstract

Prostate cancer is one of the most frequent cancers in males and commonly a disease of the older population, but it is increasingly seen among older adolescents and young adults. The common sites of metastasis of prostatic carcinoma are bones and regional lymph nodes. Testicular metastasis from prostatic carcinoma is an infrequent presentation. We report a case of a young patient with prostatic carcinoma and multiple metastases, including bilateral testis. A 40-year-old male presented with lower urinary tract voiding symptoms and back pain for three months. His prostate-specific antigen level was elevated at 13.98 ng/ml. A magnetic resonance imaging of the prostate revealed two PIRADS V lesions and metastases in multiple bones and regional lymph nodes. On follow up, the patient complained of bilateral testicular swelling and ultrasound scan of the testes revealed bilateral testicular metastasis. Fine needle aspiration cytology of right-side testicular lesion revealed malignant cells compatible with metastasis from prostate cancer. Later involvement of multilevel vertebral and skull metastases was identified by magnetic resonance imaging. A TNM1 staging of prostate cancer was made, androgen deprivation therapy followed by chemo and radiotherapy was instituted, following extensive discussion with the patient. Unfortunately the patient succumbed to the illness during the course of treatment. This case report is of a patient with rare presentation of bilateral testicular metastasis with prostate cancer in young age.

摘要

前列腺癌是男性中最常见的癌症之一,通常是一种老年人群的疾病,但在年龄较大的青少年和年轻成年人中也越来越常见。前列腺癌常见的转移部位是骨骼和区域淋巴结。前列腺癌转移至睾丸是一种罕见的表现。我们报告一例年轻的前列腺癌患者伴有多处转移,包括双侧睾丸转移。一名40岁男性出现下尿路排尿症状和背痛3个月。他的前列腺特异性抗原水平升高至13.98 ng/ml。前列腺磁共振成像显示两个前列腺影像报告和数据系统(PIRADS)5类病变以及多处骨骼和区域淋巴结转移。随访时,患者主诉双侧睾丸肿大,睾丸超声检查显示双侧睾丸转移。右侧睾丸病变的细针穿刺细胞学检查发现与前列腺癌转移相符的恶性细胞。磁共振成像后来发现了多级椎体和颅骨转移。对前列腺癌进行了TNM1分期,在与患者进行广泛讨论后,开始进行雄激素剥夺治疗,随后进行化疗和放疗。不幸的是,患者在治疗过程中因病死亡。本病例报告的是一名年轻患者,罕见地出现双侧睾丸转移的前列腺癌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a81/9568776/0fd0233fddee/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a81/9568776/494675620a86/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a81/9568776/021f7be2c4f0/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a81/9568776/0fd0233fddee/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a81/9568776/494675620a86/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a81/9568776/021f7be2c4f0/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a81/9568776/0fd0233fddee/gr3.jpg

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2
The SCARE 2020 Guideline: Updating Consensus Surgical CAse REport (SCARE) Guidelines.SCARE 2020 指南:更新共识手术病例报告(SCARE)指南。
Int J Surg. 2020 Dec;84:226-230. doi: 10.1016/j.ijsu.2020.10.034. Epub 2020 Nov 9.
3
Androgen deprivation therapy and side effects: are GnRH antagonists safer?
Editorial: Complexity of tumor microenvironment: A major culprit in cancer development.
社论:肿瘤微环境的复杂性:癌症发展的主要元凶
Front Endocrinol (Lausanne). 2022 Oct 20;13:1059885. doi: 10.3389/fendo.2022.1059885. eCollection 2022.
雄激素剥夺疗法及其副作用:促性腺激素释放激素拮抗剂更安全吗?
Asian J Androl. 2021 Jan-Feb;23(1):3-10. doi: 10.4103/aja.aja_22_20.
4
Prostate cancer in young men: An emerging young adult and older adolescent challenge.青年男性前列腺癌:新兴的青年成年和大龄青少年挑战。
Cancer. 2020 Jan 1;126(1):46-57. doi: 10.1002/cncr.32498. Epub 2019 Sep 25.
5
Chemotherapy and radiation for prostate cancer.前列腺癌的化疗与放疗。
Transl Androl Urol. 2018 Jun;7(3):390-398. doi: 10.21037/tau.2018.03.07.
6
Testicular Metastasis From Prostatic Adenocarcinoma Presenting as Recurrent Epididymo-orchitis.
Urology. 2017 Oct;108:e7-e9. doi: 10.1016/j.urology.2017.07.029. Epub 2017 Jul 28.
7
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8
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J Clin Pathol. 2015 Jul;68(7):511-5. doi: 10.1136/jclinpath-2015-202993. Epub 2015 Apr 2.
9
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10
Testicular metastases from prostate carcinoma.前列腺癌的睾丸转移。
Asian J Surg. 2010 Jul;33(3):154-6. doi: 10.1016/S1015-9584(10)60026-7.