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药剂专业人员和学生中纤维肌痛的患病率:一项横断面研究。

Prevalence of Fibromyalgia in Pharmacy Professionals and Students: A Cross-Sectional Study.

作者信息

AlAujan Shiekha S, Almalag Haya M, Omair Mohammed A

机构信息

Clinical Pharmacy Department, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

Division of Rheumatology, Department of Medicine, King Saud University, Riyadh, Saudi Arabia.

出版信息

J Pain Res. 2021 Mar 31;14:837-847. doi: 10.2147/JPR.S301916. eCollection 2021.

Abstract

BACKGROUND

The prevalence of fibromyalgia (FM) in pharmacy students and professionals is unknown. This study identifies the prevalence of FM in pharmacy students and professionals using three screening tools and factors associated with its development. Furthermore, this study assesses the level of agreement between the tools and the magnitude of the participants' responses to each item in the screening tools.

METHODS

This was a cross-sectional survey conducted on members of the Saudi Pharmaceutical Society using an online questionnaire. The participants were asked to fill three questionnaires: the London Fibromyalgia Epidemiology Study Screening Questionnaire (LFESSQ), Fibromyalgia Rapid Screening Tool (FiRST) and Fibromyalgia Survey Questionnaire (FSQ). Demographic data and factors affecting FM in pharmacy students and professionals were collected and analysed.

RESULTS

Two hundred ninety-three participants accessed the survey: most of them were Saudi (93.5%) and females (78.8%) with a mean (standard deviation) age of 29 (8) years. Furthermore, 52% of the participants had generalised body pain. The prevalence of FM using FiRST, LFESSQ Pain, LFESSQ with fatigue criteria and FSQ was 27.1%, 34.9%, 50.9% and 68.4%, respectively. Fleiss' kappa coefficient revealed fair agreement among all three screening tools (kappa = 0.350; < 0.001). After adjusting for significant variables, the resulting adjusted odds ratio of developing FM was 4.86 in people working for 41-45 h weekly (95% confidence interval [CI], 1.32-17.84; p = 0.017), 5.16 in people who frequently wake up during sleep (95% CI, 1.85-14.40; p = 0.002) and 12.99 in people with sleep apnea or other sleeping disorders (95% CI, 2.07-81.68; p = 0.006).

CONCLUSION

FM was prevalent among pharmacy students and professionals and was much more than data reported on the general population or other healthcare workers. Traditional factors along with higher working hours were identified as significant variables.

摘要

背景

药学生和药学专业人员中纤维肌痛(FM)的患病率尚不清楚。本研究使用三种筛查工具确定药学生和药学专业人员中FM的患病率及其相关因素。此外,本研究评估了这些工具之间的一致性水平以及参与者对筛查工具中每个项目的反应程度。

方法

这是一项对沙特制药协会成员进行的横断面调查,采用在线问卷形式。参与者被要求填写三份问卷:伦敦纤维肌痛流行病学研究筛查问卷(LFESSQ)、纤维肌痛快速筛查工具(FiRST)和纤维肌痛调查问卷(FSQ)。收集并分析了药学生和药学专业人员的人口统计学数据以及影响FM的因素。

结果

293名参与者参与了调查:他们大多是沙特人(93.5%),女性(78.8%),平均(标准差)年龄为29(8)岁。此外,52%的参与者有全身疼痛。使用FiRST、LFESSQ疼痛量表、符合疲劳标准的LFESSQ以及FSQ得出的FM患病率分别为27.1%、34.9%、50.9%和68.4%。Fleiss卡方系数显示,所有三种筛查工具之间的一致性一般(卡方 = 0.350;< 0.001)。在对显著变量进行调整后,每周工作41 - 45小时的人患FM的调整后优势比为4.86(95%置信区间[CI],1.32 - 17.84;p = 0.017),睡眠中经常醒来的人这一数值为5.16(95% CI,1.85 - 14.40;p = 0.002),患有睡眠呼吸暂停或其他睡眠障碍的人这一数值为12.99(95% CI,2.07 - 81.68;p = 0.006)。

结论

FM在药学生和药学专业人员中普遍存在,且高于一般人群或其他医护人员报告的数据。传统因素以及较长的工作时间被确定为显著变量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbef/8020587/3a4f4ff84bfa/JPR-14-837-g0001.jpg

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