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F1000Res. 2016 Aug 17;5. doi: 10.12688/f1000research.8863.1. eCollection 2016.
2
EULAR revised recommendations for the management of fibromyalgia.EULAR 修订的纤维肌痛管理建议。
Ann Rheum Dis. 2017 Feb;76(2):318-328. doi: 10.1136/annrheumdis-2016-209724. Epub 2016 Jul 4.
3
Prescription of Long-Acting Opioids and Mortality in Patients With Chronic Noncancer Pain.长效阿片类药物处方与慢性非癌性疼痛患者的死亡率
JAMA. 2016 Jun 14;315(22):2415-23. doi: 10.1001/jama.2016.7789.
4
Decrease of fear avoidance beliefs following person-centered progressive resistance exercise contributes to reduced pain disability in women with fibromyalgia: secondary exploratory analyses from a randomized controlled trial.以人为主的渐进性抗阻运动后恐惧回避信念的降低有助于减轻纤维肌痛女性的疼痛残疾:一项随机对照试验的二次探索性分析。
Arthritis Res Ther. 2016 May 21;18(1):116. doi: 10.1186/s13075-016-1007-0.
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The opioid epidemic and the long-term opioid therapy for chronic noncancer pain revisited: a transatlantic perspective.再谈阿片类药物流行与慢性非癌性疼痛的长期阿片类药物治疗:跨大西洋视角
Pain Manag. 2016;6(3):249-63. doi: 10.2217/pmt.16.5. Epub 2016 Mar 18.
6
Variability of gait, bilateral coordination, and asymmetry in women with fibromyalgia.纤维肌痛女性的步态变异性、双侧协调性和不对称性。
Gait Posture. 2016 Mar;45:41-4. doi: 10.1016/j.gaitpost.2016.01.008. Epub 2016 Jan 12.
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Effects of testosterone replacement on metabolic and inflammatory markers in men with opioid-induced androgen deficiency.睾酮替代疗法对阿片类药物所致雄激素缺乏男性患者代谢及炎症标志物的影响。
Clin Endocrinol (Oxf). 2016 Aug;85(2):232-8. doi: 10.1111/cen.13049. Epub 2016 Apr 4.
8
Irritable bowel syndrome subtypes: Clinical and psychological features, body mass index and comorbidities.肠易激综合征亚型:临床与心理特征、体重指数及合并症
Rev Esp Enferm Dig. 2016 Feb;108(2):59-64. doi: 10.17235/reed.2015.3979/2015.
9
Low vitamin D and the risk of developing chronic widespread pain: results from the European male ageing study.维生素D水平低与慢性广泛性疼痛的发生风险:欧洲男性老龄化研究结果
BMC Musculoskelet Disord. 2016 Jan 16;17:32. doi: 10.1186/s12891-016-0881-6.
10
Altered fMRI resting-state connectivity in individuals with fibromyalgia on acute pain stimulation.纤维肌痛患者在急性疼痛刺激下功能磁共振成像静息态连接性的改变
Eur J Pain. 2016 Aug;20(7):1079-89. doi: 10.1002/ejp.832. Epub 2016 Jan 15.

纤维肌痛的争议与挑战:综述与建议

Controversies and challenges in fibromyalgia: a review and a proposal.

作者信息

Cohen Helen

机构信息

Royal National Orthopaedic Hospital, Stanmore, Brockley Hill, Stanmore, Middlesex, HA7 4LP, UK.

出版信息

Ther Adv Musculoskelet Dis. 2017 May;9(5):115-127. doi: 10.1177/1759720X17699199. Epub 2017 Mar 26.

DOI:10.1177/1759720X17699199
PMID:28458723
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5394529/
Abstract

Fibromyalgia (FM) is the most commonly encountered chronic widespread pain (CWP) condition in rheumatology. In comparison to inflammatory arthritis (IA), it can seem ill defined with no clear understanding of the pathology and therefore no specific targeted treatment. This inevitably raises controversies and challenges. However, this is an outdated view perpetuated by poor teaching of pain at undergraduate and postgraduate levels, and the perennial problem of advances in relevant cross-speciality knowledge penetrating speciality silos. Research has provided a better understanding of the aetiopathology and FM is now regarded as a centralized pain state. Effective treatment is possible utilizing a multidisciplinary approach combining nonpharmacologic and pharmacologic treatments rooted in a biopsychosocial model. This article will provide a review of the mechanisms, diagnosis and treatment of FM, focus on some ongoing contentious issues and propose a change to the diagnostic terminology.

摘要

纤维肌痛(FM)是风湿病学中最常见的慢性广泛性疼痛(CWP)病症。与炎症性关节炎(IA)相比,它似乎定义不明确,对其病理没有清晰的认识,因此也没有特定的靶向治疗方法。这不可避免地引发了争议和挑战。然而,这是一种过时的观点,因本科和研究生阶段疼痛教学不佳以及相关跨专业知识进步难以渗透到专业领域这一长期问题而持续存在。研究已使人们对病因病理学有了更好的理解,现在纤维肌痛被视为一种中枢性疼痛状态。采用基于生物心理社会模型的多学科方法,结合非药物和药物治疗,有效治疗是可行的。本文将对纤维肌痛的机制、诊断和治疗进行综述,关注一些当前有争议的问题,并提议改变诊断术语。