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拖出吻合技术用于回肠原位新膀胱重建术后尿流参数的临床研究。

The clinical study of urinary flow parameters after drag-and-bond anastomosis for ileal orthotopic neobladder reconstruction.

机构信息

Jiangxi Medical College, Nanchang University, Nanchang, 330006, Jiangxi, China.

Department of Urology, Jiangxi Provincial People's Hospital, No.92Aiguo Road, Donghu District, Nanchang, 330006, Jiangxi, China.

出版信息

Int Urol Nephrol. 2024 Aug;56(8):2615-2621. doi: 10.1007/s11255-024-04015-7. Epub 2024 Mar 19.

Abstract

AIM

To assess the viability of this procedure in laparoscopic radical cystectomy with ileal orthotopic neobladder reconstruction, the objective of this study is to examine the relationship between urinary flow parameters of urethral drag-and-bond anastomosis in the reconstruction of the ileal orthotopic neobladder.

METHODS

36 patients with bladder cancer underwent laparoscopic radical cystectomy with ileal orthotopic neobladder reconstruction at Jiangxi provincial people's hospital between June 2016 and January 2021,16 patients underwent intermittent urethral anastomosis, while 20 patients underwent neobladder-urethral drag-and-bond anastomosis. The maximum bladder capacity, residual urine output, maximum urinary flow rate, and outlet morphology of the new bladder neck were all monitored throughout postoperative follow-up regularly.

RESULTS

There was no significant difference between the urethral drag-and-bond anastomosis group (group A) and the conventional anastomosis group (group B) at 3 months and 12 months after surgery, and the maximum bladder capacity (3 months, 488.35 ± 51.56 ml vs 481.06 ± 40.61 ml, t = -0.462, P = 0.647; 12 months, 496.35 ± 51.09 ml vs 476.56 ± 56.33 ml, t = -1.103, P = 0.278), residual urine output (3 months, 44.15 ± 24.12 ml vs 38.69 ± 21.82 ml, t = -0.704, P = 0.486;12 months, 49.65 ± 26.95 ml vs 36.75 ± 21.96 ml, t = -1.546, P = 0.131) and maximum urine flow rate (3 months, 12.36 ± 2.63 ml/s vs 13.60 ± 2.82 ml/s, t = 1.361, P = 0.182;12 months, 12.18 ± 3.14 ml/s vs 11.13 ± 3.01 ml/s, t = -1.004, P = 0.322) of the two groups were not significant (P > 0.05). The new bladder outlet morphology was not distorted in group A patients, the continuity was good, and there were fewer associated complications.

CONCLUSIONS

There was no significant difference in postoperative urodynamic parameters between the urethral drag-and-bond anastomosis group and the conventional anastomosis group, and the postoperative new bladder outlet was in good shape, with clinical significance.

摘要

目的

评估该方法在腹腔镜根治性膀胱切除术联合回肠原位新膀胱重建中的可行性,本研究旨在研究回肠原位新膀胱重建中尿道拖曳和吻合的尿流参数与新膀胱颈出口形态之间的关系。

方法

2016 年 6 月至 2021 年 1 月,江西省人民医院对 36 例膀胱癌患者行腹腔镜根治性膀胱切除术联合回肠原位新膀胱重建,其中 16 例行间歇性尿道吻合术,20 例行新膀胱-尿道拖曳吻合术。术后定期随访,监测新膀胱最大膀胱容量、残余尿量、最大尿流率和新膀胱颈出口形态。

结果

术后 3 个月和 12 个月,尿道拖曳吻合组(A 组)和常规吻合组(B 组)在最大膀胱容量(3 个月:488.35±51.56ml 比 481.06±40.61ml,t=-0.462,P=0.647;12 个月:496.35±51.09ml 比 476.56±56.33ml,t=-1.103,P=0.278)、残余尿量(3 个月:44.15±24.12ml 比 38.69±21.82ml,t=-0.704,P=0.486;12 个月:49.65±26.95ml 比 36.75±21.96ml,t=-1.546,P=0.131)和最大尿流率(3 个月:12.36±2.63ml/s 比 13.60±2.82ml/s,t=1.361,P=0.182;12 个月:12.18±3.14ml/s 比 11.13±3.01ml/s,t=-1.004,P=0.322)方面差异均无统计学意义(P>0.05)。A 组患者新膀胱出口形态无变形,连续性良好,相关并发症较少。

结论

尿道拖曳吻合组与常规吻合组术后尿动力学参数无显著差异,术后新膀胱出口形态良好,具有临床意义。

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