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小儿胰胆疾病的内镜超声检查:单中心试验

Endoscopic Ultrasonography in Pediatric Patients with Pancreatobiliary Disease: Single-Center Trial.

作者信息

Demirbaş Fatma, Kaymazlı Mustafa, Çaltepe Gönül, Abbasguliyev Hasan, Kalaycı Ayhan Gazi, Bektaş Ahmet

机构信息

Department of Pediatric Gastroenterology, Hepatology and Nutrition, Ondokuz Mayıs University Faculty of Medicine, Samsun, Turkey.

Department of Gastroenterology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Turkey.

出版信息

Pediatr Gastroenterol Hepatol Nutr. 2021 Mar;24(2):164-172. doi: 10.5223/pghn.2021.24.2.164. Epub 2021 Mar 4.

DOI:10.5223/pghn.2021.24.2.164
PMID:33833972
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8007838/
Abstract

PURPOSE

The use of Endoscopic ultrasonography (EUS) in pediatric patients is not as common as in adults. The aim of this study is to evaluate the role of EUS in the diagnosis of pancreatobiliary disease in childhood.

METHODS

Between December 2016 and January 2018, the findings of patients who underwent EUS were evaluated retrospectively.

RESULTS

Of the 41 patients included in the study 25 were girls (61.0%), mean age was 12.2±4.2 years. EUS was performed for biliary colic in 21 (51.2%), for recurrent pancreatitis in 12 (29.2%), for cholecystitis/cholangitis in 5 (12.2%), and for acute pancreatitis in 3 (7.4%) patients. EUS had a significant clinical effect in the decision of treatment and follow-up of 6/21 biliary colic cases, in diagnosis and follow-up of 6/12 recurrent pancreatitis cases, in decision-making and monitoring of invasive procedures (ERCP/surgery) of 3/5 acute cholecystitis/cholangitis and 2/3 of acute pancreatitis cases as well as in follow-up of the other cases. The effectiveness of EUS in determining direct treatment and invasive intervention was 43.9%. None of the patients had complications related to the EUS procedure.

CONCLUSION

Although current guidelines show that EUS can be used in pediatric patients, this is limited to a few published studies. In this study, it is shown that EUS is a safe method for the diagnosis, follow-up and treatment of common pancreatobiliary pathologies in childhood.

摘要

目的

内镜超声检查(EUS)在儿科患者中的应用不如在成人中常见。本研究的目的是评估EUS在儿童胰胆疾病诊断中的作用。

方法

回顾性评估2016年12月至2018年1月期间接受EUS检查的患者的检查结果。

结果

本研究纳入的41例患者中,25例为女孩(61.0%),平均年龄为12.2±4.2岁。进行EUS检查的原因包括:21例(51.2%)为胆绞痛,12例(29.2%)为复发性胰腺炎,5例(12.2%)为胆囊炎/胆管炎,3例(7.4%)为急性胰腺炎。EUS在以下方面具有显著临床效果:21例胆绞痛病例中有6例在治疗决策和随访中,12例复发性胰腺炎病例中有6例在诊断和随访中,5例急性胆囊炎/胆管炎中有3例以及3例急性胰腺炎中有2例在侵入性操作(内镜逆行胰胆管造影术/手术)的决策和监测中,以及在其他病例的随访中。EUS在确定直接治疗和侵入性干预方面的有效性为43.9%。所有患者均未出现与EUS检查相关的并发症。

结论

尽管目前的指南表明EUS可用于儿科患者,但这仅限于少数已发表的研究。本研究表明,EUS是诊断、随访和治疗儿童常见胰胆疾病的一种安全方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57eb/8007838/4c902ac7264e/pghn-24-164-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57eb/8007838/e4ae370edd59/pghn-24-164-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57eb/8007838/17b589c8fe5b/pghn-24-164-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57eb/8007838/4c902ac7264e/pghn-24-164-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57eb/8007838/e4ae370edd59/pghn-24-164-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57eb/8007838/17b589c8fe5b/pghn-24-164-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57eb/8007838/4c902ac7264e/pghn-24-164-g003.jpg

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2
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Pancreas. 2019 Mar;48(3):350-355. doi: 10.1097/MPA.0000000000001243.
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Endoscopic ultrasound in pediatric population: a comprehensive review of the literature.
儿科人群中的内镜超声:文献综述
Acta Biomed. 2018 Dec 17;89(9-S):33-39. doi: 10.23750/abm.v89i9-S.7876.
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Etiology and Outcome of Cholelithiasis in Turkish Children.土耳其儿童胆结石的病因及转归
Indian Pediatr. 2018 Mar 15;55(3):216-218. Epub 2017 Dec 14.
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The emerging role of endoscopic ultrasound for pancreaticobiliary diseases in the pediatric population.儿童人群胰腺胆道疾病内镜超声的新兴作用。
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