Jiang Xin-Quan
Dept. of Prosthodontics, Shanghai Ninth People,s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine; College of Stomatology, Shanghai Jiao Tong University; National Clinical Research Center for Oral Diseases; Shanghai Engineering Research Center of Advanced Dental Technology and Materials; Shanghai Key Laboratory of Stomatology; Shanghai Research Institute of Stomatology, Shanghai 200011, China.
Hua Xi Kou Qiang Yi Xue Za Zhi. 2021 Apr 1;39(2):123-128. doi: 10.7518/hxkq.2021.02.001.
Oromaxillofacial hard tissue defects is still a difficult problem in clinical treatment. Regeneration of oromaxillofacial hard tissue based on tissue engineering technology has a good clinical application prospect. The functional modification of scaffolds is one of key factors that influence the outcome of tissue regeneration. The biomimetic design of biomaterials through simulating the natural structure and composition of oromaxillofacial hard tissue has gradually become a research hotspot due to its advantages of simplicity and efficiency. In this article, the biomimetic modification of biomaterials for oromaxillofacial hard tissue regeneration is reviewed, expecting to provide a new idea for the treatment of oromaxillofacial hard tissue defect.
口腔颌面部硬组织缺损仍是临床治疗中的难题。基于组织工程技术的口腔颌面部硬组织再生具有良好的临床应用前景。支架的功能修饰是影响组织再生效果的关键因素之一。通过模拟口腔颌面部硬组织的天然结构和组成对生物材料进行仿生设计,因其简便高效的优点逐渐成为研究热点。本文对用于口腔颌面部硬组织再生的生物材料仿生修饰进行综述,以期为口腔颌面部硬组织缺损的治疗提供新思路。