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2018 年 12 月至 2019 年 3 月,挪威爆发了由异国干水果引起的阿格贝尼疫情,临床症状严重。

Exotic dried fruits caused Agbeni outbreak with severe clinical presentation, Norway, December 2018 to March 2019.

机构信息

Norwegian Institute of Public Health, Oslo, Norway.

European Public Health Microbiology Training Programme (EUPHEM), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.

出版信息

Euro Surveill. 2021 Apr;26(14). doi: 10.2807/1560-7917.ES.2021.26.14.2000221.

DOI:10.2807/1560-7917.ES.2021.26.14.2000221
PMID:33834962
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8034060/
Abstract

We describe an outbreak of Agbeni sequence type (ST)2009 infections in Norway. Between 31 December 2018 and 16 March 2019, 56 cases (33 female and 23 male; median age: 50 years, range: 2-91) were reported, of which 21 were hospitalised. Cases were defined as people living in Norway, with laboratory-confirmed infection with . Agbeni ST2009 and cluster type (CT)2489, reported between 31 December 2018 and 30 March 2019. We conducted a case-control study, with three controls per case (matched by age, sex and municipality), using the Norwegian National Registry. Cases were more likely to have consumed a commercial mix of dried exotic fruits than controls (cases = 8, controls = 31; odds ratio: 50; 95% confidence interval: 3-2,437). The outbreak strain was confirmed by whole genome sequencing (WGS) and was isolated from the fruit mix consumed by cases, resulting in withdrawal from the market on 6 March 2019.The fruit mix consisted of fruits from different countries and continents. It was packed in Italy and distributed to several European countries, including Norway. However, no other countries reported cases. This outbreak highlights that dried fruits could represent a risk in terms of food-borne infections, which is of particular concern in ready-to-eat products.

摘要

我们描述了挪威爆发的 Agbeni 序列型(ST)2009 感染疫情。在 2018 年 12 月 31 日至 2019 年 3 月 16 日期间,报告了 56 例病例(33 名女性和 23 名男性;中位数年龄为 50 岁,范围为 2-91 岁),其中 21 例住院。病例定义为居住在挪威、实验室确诊感染. Agbeni ST2009 和聚类型(CT)2489 的人,报告时间为 2018 年 12 月 31 日至 2019 年 3 月 30 日之间。我们进行了一项病例对照研究,每个病例匹配 3 名对照(按年龄、性别和市匹配),使用挪威国家登记处。病例比对照组更有可能食用了一种商业混合干奇异果(病例=8,对照组=31;优势比:50;95%置信区间:3-2437)。爆发菌株通过全基因组测序(WGS)确认,并从病例食用的水果混合物中分离出来,导致该水果混合物于 2019 年 3 月 6 日撤出市场。该水果混合物由来自不同国家和大陆的水果组成。它在意大利包装,并分发到包括挪威在内的几个欧洲国家,但其他国家没有报告病例。此次疫情突显了干水果可能存在食源性感染风险,尤其是在即食产品中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/875f/8034060/b729cce1f4fd/2000221-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/875f/8034060/2de7fdc28174/2000221-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/875f/8034060/649b887575f3/2000221-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/875f/8034060/b729cce1f4fd/2000221-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/875f/8034060/2de7fdc28174/2000221-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/875f/8034060/649b887575f3/2000221-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/875f/8034060/b729cce1f4fd/2000221-f3.jpg

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