Department of Traumatic Orthopaedics, Peking University People's Hospital, Beijing, China.
Institute of Trauma and Nerve Regeneration, Peking University People's Hospital, Beijing, China.
PLoS One. 2021 Apr 9;16(4):e0250009. doi: 10.1371/journal.pone.0250009. eCollection 2021.
The objective of this study is to establish an ankylosing spondylitis (AS) thoracolumbar fracture finite element (FE) model and provide a proper posterior fixation choice from the biomechanical perspective. The ankylosing spondylitis T9-L5 FE model was built and the range of motion (ROM) was compared to previous studies. The L1 transverse fracture was simulated and was separately fixed by five different patterns. The pull force and yielding force of the screws, the von Mises stress of the internal fixation, and the displacement of fracture site were analyzed to evaluate the proper fixation pattern for thoracolumbar fracture of AS. ROM of AS model was obviously restricted comparing to the normal vertebral experimental data. All the fixation patterns can stabilize the fracture. At least four levels of fixation can reduce the von Mises stress of the internal fixation. Four levels fixation has a higher pull force than the six levels fixation. Skipped level fixation did not reduce the stress, pull force and yielding force. The kyphosis correction did not change the biomechanical load. At least 4 levels fixation was needed for AS thoracolumbar fracture. The cemented screws should be chosen in 4 levels fixation to increase the holding of the screws. The skipped fixation has no advantage. The kyphosis correction can be chosen after weighing the pros and cons.
本研究旨在建立强直性脊柱炎(AS)胸腰椎骨折有限元(FE)模型,并从生物力学角度为后固定提供合理选择。建立了 AS 的 T9-L5 FE 模型,并与之前的研究进行了比较。模拟了 L1 横突骨折,并分别采用五种不同的固定方式进行固定。分析了螺钉的拔出力和屈服力、内固定的 von Mises 应力以及骨折部位的位移,以评估 AS 胸腰椎骨折的合适固定方式。与正常椎体的实验数据相比,AS 模型的活动度明显受限。所有固定方式均可稳定骨折。至少四个节段的固定可降低内固定的 von Mises 应力。与六节段固定相比,四节段固定的拔出力更高。跳节固定并不能降低应力、拔出力和屈服力。后凸矫正并不能改变生物力学负荷。AS 胸腰椎骨折至少需要 4 个节段的固定。在 4 个节段固定中应选择骨水泥螺钉,以增加螺钉的固定强度。跳节固定没有优势。应权衡利弊后选择后凸矫正。