Servicio de Cardiología, Complejo Hospitalario Universitario de A Coruña, Instituto de Investigación Biomédica de A Coruña (INIBIC), A Coruña, España.
Servicio de Traumatología, Complejo Hospitalario Universitario de Ferrol, Ferrol, A Coruña, España.
Med Clin (Barc). 2021 Jun 25;156(12):615-621. doi: 10.1016/j.medcli.2021.01.015. Epub 2021 Apr 6.
Autoimmune rheumatic diseases are inflammatory disorders that can involve multiple organs, including the heart. The high risk of cardiovascular pathology in these patients is not only due to traditional cardiovascular risk factors, but also to chronic inflammation and autoimmunity. All cardiac structures may be affected during the course of systemic autoimmune diseases (valves, the conduction system, the myocardium, endocardium and pericardium, and coronary arteries), and the cardiac complications have a variety of clinical manifestations. As these are all associated with an unfavourable prognosis, it is essential to detect subclinical cardiac involvement in asymptomatic systemic autoimmune disease patients and begin adequate management and treatment early. In this review, we examine the multiple cardiovascular manifestations in patients with rheumatological disorders and available management strategies.
自身免疫性风湿病是一种炎症性疾病,可累及多个器官,包括心脏。这些患者发生心血管疾病的风险较高,不仅与传统的心血管危险因素有关,还与慢性炎症和自身免疫有关。在系统性自身免疫性疾病过程中,所有心脏结构都可能受到影响(瓣膜、传导系统、心肌、心内膜和心包以及冠状动脉),并且心脏并发症具有多种临床表现。由于这些都与不良预后相关,因此检测无症状系统性自身免疫性疾病患者的亚临床心脏受累并及早进行适当的管理和治疗至关重要。在这篇综述中,我们检查了风湿性疾病患者的多种心血管表现和可用的管理策略。