Department of Medicine, Division of Gastroenterology, Hepatology, and Nutrition, Vanderbilt University Medical Center, 1660 The Vanderbilt Clinic, Nashville, TN 37232, USA.
Department of Medicine, Division of Gastroenterology and Hepatology, Northwestern University Feinberg School of Medicine, 676 North St Clair, Suite 1400, Chicago, IL 60611, USA; Department of Preventive Medicine, Division of Epidemiology, Northwestern University Feinberg School of Medicine, 676 North St Clair, Suite 1400, Chicago, IL 60611, USA.
Clin Liver Dis. 2021 May;25(2):471-481. doi: 10.1016/j.cld.2021.01.012. Epub 2021 Mar 10.
Cirrhotic cardiomyopathy (CCM) connotes systolic and/or diastolic dysfunction in patients with end-stage liver disease in the absence of prior heart disease. Its prevalence is variable across different studies but recent data suggest that CCM may affect up to one third of liver transplant candidates. The etiology of CCM is multifactorial. CCM defining features were recently revised to improve the diagnostic and prognostic yield of CCM criteria and inform candidate selection for liver transplantation. CCM appears to increase the risk for unfavorable outcomes pre- and post-transplant. Close clinical and echocardiographic follow-up of patients with CCM may mitigate adverse cardiac outcomes.
肝硬化性心肌病（CCM）是指在没有先前心脏病的情况下，终末期肝病患者出现收缩和/或舒张功能障碍。其在不同研究中的患病率各不相同，但最近的数据表明，CCM 可能影响多达三分之一的肝移植候选者。CCM 的病因是多因素的。最近修订了 CCM 的定义特征，以提高 CCM 标准的诊断和预后效果，并为肝移植候选者的选择提供信息。CCM 似乎增加了移植前后不良结局的风险。对 CCM 患者进行密切的临床和超声心动图随访，可能会减轻不良心脏结局的发生。
