AlAmari Kholoud, Zahlan Abdullah M, Albawardi Esam, Dababo Mohammed, Alotaibi Naif H
Department of Otolaryngology-Head & Neck Surgery, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Int J Surg Case Rep. 2021 May;82:105859. doi: 10.1016/j.ijscr.2021.105859. Epub 2021 Apr 1.
Pleomorphic adenoma is the most common benign salivary gland neoplasm. The majority of cases occur in the major salivary glands; however, they can also originate from the minor salivary glands. The nasopharynx is an uncommon site, but it has been reported in the literature. The characteristic difference of our report from the literature is the young age of our patient and his previous unremarkable medical or surgical history. The objective of this report is to present a case of salivary gland pleomorphic adenoma, discuss radiological and histopathological findings and treatment options.
Herein we report a case of a 25-year-old male patient presenting with a long-term history of snoring, mouth breathing, and progressive left nasal obstruction. After examining the patient and confirming the diagnosis, patient successfully underwent tumor resection using a combined transnasal/transoral endoscopic approach with no complications following surgery and significant improvement of the previously reported symptoms.
Pleomorphic adenoma of the minor salivary glands can occur anywhere throughout the distribution sites of these glands such as: along the upper aerodigestive tract, parapharyngeal fat spaces, soft palate, the sinonasal, and nasopharyngeal areas.
The occurrence of pleomorphic adenoma in uncommon sites has been reported in the literature, and the nasopharynx is considered to be one of these uncommon sites. The mainstay of treatment for nasopharyngeal pleomorphic adenoma is surgical excision as they can grow to giant sizes if left untreated.
多形性腺瘤是最常见的涎腺良性肿瘤。大多数病例发生于大涎腺;然而,它们也可起源于小涎腺。鼻咽部是一个不常见的部位,但文献中已有报道。我们的报告与文献的特征性差异在于我们患者的年轻年龄以及他既往无显著的内科或外科病史。本报告的目的是呈现一例涎腺多形性腺瘤病例,讨论其影像学和组织病理学表现以及治疗选择。
在此我们报告一例25岁男性患者,有长期打鼾、口呼吸及进行性左侧鼻塞病史。在对患者进行检查并确诊后,患者成功接受了经鼻/经口联合内镜手术切除肿瘤,术后无并发症,先前报告的症状有显著改善。
小涎腺多形性腺瘤可发生于这些腺体分布的任何部位,如:沿上消化道呼吸道、咽旁脂肪间隙、软腭、鼻窦和鼻咽区域。
文献中已报道多形性腺瘤在不常见部位的发生,鼻咽部被认为是这些不常见部位之一。鼻咽部多形性腺瘤的主要治疗方法是手术切除,因为如果不治疗,它们可能会长到巨大尺寸。