Service ORL et chirurgie cervico-faciale, centre hospitalier intercommunal André-Grégoire, 56, boulevard de Boissière, 93130 Montreuil, France.
Service ORL et chirurgie cervico-faciale, centre hospitalier intercommunal André-Grégoire, 56, boulevard de Boissière, 93130 Montreuil, France.
Eur Ann Otorhinolaryngol Head Neck Dis. 2014 Apr;131(2):139-41. doi: 10.1016/j.anorl.2013.03.007. Epub 2013 Oct 15.
Pleomorphic adenoma is the most common benign tumour of the salivary glands. The major salivary glands are most commonly involved, or more rarely accessory salivary glands, especially the oral cavity. Other locations, such as the nasal cavity, paranasal sinuses or upper aerodigestive tract, are exceptional.
A 26-year-old female presented with right-sided nasal obstruction. Radiology found a lesion involving the anterior third of the nasal septum. The patient underwent complete surgical resection of the tumour via an endonasal approach. Histological examination found a mixed cellular component (epithelial and myoepithelial) and mesenchymatous tissue with chondromyxoid stroma, enabling diagnosis of a typical pleomorphic adenoma.
DISCUSSION/CONCLUSION: Pleomorphic adenoma is exceptional in the nasal cavity, with only a few cases reported in the literature. Although benign, the risk of local recurrence, malignant transformation and metastasis requires close long-term follow-up.
多形性腺瘤是唾液腺最常见的良性肿瘤。大涎腺最常受累，或罕见地累及副涎腺，特别是口腔。其他部位，如鼻腔、副鼻窦或上呼吸道，较为罕见。
一名 26 岁女性因右侧鼻腔阻塞就诊。影像学检查发现病变累及鼻中隔前 1/3。患者经鼻内入路行肿瘤完全切除术。组织学检查发现混合细胞成分（上皮和肌上皮）和间叶组织伴软骨黏液样基质，诊断为典型的多形性腺瘤。
讨论/结论：多形性腺瘤在鼻腔中较为罕见，文献中仅报道了少数几例。尽管为良性，但存在局部复发、恶性转化和转移的风险，需要密切的长期随访。
