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COVID-19 感染康复后的肺纤维化后遗症。

Lung Fibrosis Sequelae After Recovery from COVID-19 Infection.

机构信息

Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia-Persahabatan Hospital, Jakarta, Indonesia.

Lung Clinic, Eka Hospital Cibubur, West Java, Indonesia.

出版信息

J Infect Dev Ctries. 2021 Mar 31;15(3):360-365. doi: 10.3855/jidc.13686.

DOI:10.3855/jidc.13686
PMID:33839710
Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus that causes coronavirus diseases 2019 (COVID-19). The SARS-CoV-2 is very contagious and nobody is known to be immune to it. The post-infected lung would leave a scar known as fibrosis, a scar tissue. A study from Wuhan, China suggested the development of fibrosis, though it was too early to label these lung changes as irreversible fibrosis in a time range of 3 weeks. The occurrence of fibrosis indicates a chronic infection which greatly contributes to the hallmark symptom of COVID-19 induced ARDS such as shortness of breath and chest pain. However, many of those studies have not yet explained the condition of the patient's lung after total recovery from the COVID-19. This report demonstrates the clinical symptoms, chest CT scan, spirometry, and blood gas analysis of patient after total recovery from the COVID-19 with appearance lung fibrosis.

摘要

严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)是一种新型冠状病毒,可引起 2019 年冠状病毒病(COVID-19)。SARS-CoV-2 的传染性很强,目前还没有人对其具有免疫力。感染后的肺部会留下疤痕,称为纤维化,这是一种疤痕组织。来自中国武汉的一项研究表明存在纤维化的发展,尽管在 3 周的时间范围内将这些肺部变化标记为不可逆转的纤维化还为时过早。纤维化的发生表明存在慢性感染,这极大地促成了 COVID-19 引起的 ARDS 的标志性症状,如呼吸急促和胸痛。然而,许多研究尚未解释 COVID-19 完全康复后患者肺部的情况。本报告展示了 COVID-19 完全康复后出现肺纤维化患者的临床症状、胸部 CT 扫描、肺量计检查和血气分析。

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