《静脉注射免疫球蛋白在儿童血液系统/肿瘤性疾病中应用的儿科专家共识》
[Pediatric expert consensus on the application of intravenous immunoglobulin in children with hematological/neoplastic diseases].
出版信息
Zhongguo Dang Dai Er Ke Za Zhi. 2021 Apr;23(4):319-327. doi: 10.7499/j.issn.1008-8830.2101174.
Abstract
Intravenous immunoglobulin (IVIG) has been widely used in chemotherapy for hematological malignancies, targeted therapy, and hematopoietic stem cell transplantation; however, there are still no available guidelines or consensus statements on the application of IVIG in pediatric hematological/neoplastic diseases at present in China and overseas. This consensus is developed based on the research advances in the application of IVIG in pediatric hematological/neoplastic diseases across the world and provides detailed recommendations for the clinical application of IVIG in pediatric hematological/neoplastic diseases and the prevention and treatment of related adverse reactions.
摘要
静脉注射免疫球蛋白（IVIG）已广泛应用于血液系统恶性肿瘤的化疗、靶向治疗及造血干细胞移植；然而，目前国内外尚无关于IVIG在儿童血液/肿瘤性疾病中应用的可用指南或共识声明。本共识基于全球IVIG在儿童血液/肿瘤性疾病应用的研究进展制定，为IVIG在儿童血液/肿瘤性疾病中的临床应用及相关不良反应的防治提供了详细建议。
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[Pediatric expert consensus on the application of intravenous immunoglobulin in children with hematological/neoplastic diseases].《静脉注射免疫球蛋白在儿童血液系统/肿瘤性疾病中应用的儿科专家共识》
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本文引用的文献
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Haematologica. 2020 Jul;105(7):1791-1801. doi: 10.3324/haematol.2019.230771. Epub 2020 May 7.
2
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J Blood Med. 2019 Dec 9;10:405-415. doi: 10.2147/JBM.S189176. eCollection 2019.
3
Updated international consensus report on the investigation and management of primary immune thrombocytopenia.更新的原发性免疫性血小板减少症的调查和管理国际共识报告。
Blood Adv. 2019 Nov 26;3(22):3780-3817. doi: 10.1182/bloodadvances.2019000812.
4
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Blood Rev. 2019 Nov;38:100596. doi: 10.1016/j.blre.2019.100596. Epub 2019 Aug 7.
5
Guidelines for the management of cytomegalovirus infection in patients with haematological malignancies and after stem cell transplantation from the 2017 European Conference on Infections in Leukaemia (ECIL 7).血液病患者和造血干细胞移植后巨细胞病毒感染管理指南，源自 2017 年白血病感染的欧洲会议（ECIL 7）。
Lancet Infect Dis. 2019 Aug;19(8):e260-e272. doi: 10.1016/S1473-3099(19)30107-0. Epub 2019 May 29.
6
Human parvovirus B19 in solid organ transplantation: Guidelines from the American society of transplantation infectious diseases community of practice.人类细小病毒 B19 在实体器官移植中的作用：美国移植感染病学会实践社区指南。
Clin Transplant. 2019 Sep;33(9):e13535. doi: 10.1111/ctr.13535. Epub 2019 Apr 11.
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Biol Blood Marrow Transplant. 2019 Mar;25(3):e76-e85. doi: 10.1016/j.bbmt.2018.12.068. Epub 2018 Dec 18.
8
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Pediatr Blood Cancer. 2018 Dec;65(12):e27348. doi: 10.1002/pbc.27348. Epub 2018 Sep 11.
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