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人类呼吸道纤毛的方向。

Orientation of human respiratory cilia.

作者信息

Rautiainen M E

机构信息

Department of Otorhinolaryngology, University of Kuopio, Finland.

出版信息

Eur Respir J. 1988 Mar;1(3):257-61.

PMID:3384079
Abstract

Ciliary orientation was studied on the respiratory epithelium of the nasal cavity or the sphenoidal sinus of ten adult nonsmokers without respiratory disease. The ciliary orientation was evaluated from micrographs by measuring the angle between the plane defined by the central tubules and reference line (with a semiautomatic image analyser (IBAS I]. The standard deviation of the angles of cilia population was counted in every field. The standard deviation of the measurements described the ciliary alignment. It varied from 12.1-41.2 degrees. The mean standard deviation was 27.3 +/- 7.4 degrees. 58% of all measured cilia were within +/- 0-20 degrees of the mean and 85% of cilia were within +/- degrees. However, a few cilia or small groups of cilia were found in most fields which differed dramatically from the main orientation. The size of these groups was always less than ten cilia. On the normal respiratory epithelium the standard deviation of ciliary orientation varies between +/- 10-40 degrees (at about 97% probability). For diagnostic conclusions more than 60 cilia should be measured.

摘要

对10名无呼吸系统疾病的成年不吸烟者鼻腔或蝶窦的呼吸上皮细胞的纤毛方向进行了研究。通过测量中央微管定义的平面与参考线之间的角度(使用半自动图像分析仪(IBAS I)),从显微照片评估纤毛方向。在每个视野中计算纤毛群体角度的标准差。测量的标准差描述了纤毛的排列情况。其范围为12.1 - 41.2度。平均标准差为27.3 +/- 7.4度。所有测量的纤毛中有58%在平均值的+/- 0 - 20度范围内,85%的纤毛在+/- 度范围内。然而,在大多数视野中发现了一些与主要方向显著不同的少数纤毛或小群纤毛。这些群体的大小总是小于10根纤毛。在正常呼吸上皮细胞上,纤毛方向的标准差在+/- 10 - 40度之间变化(概率约为97%)。为得出诊断结论,应测量60根以上的纤毛。

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Orientation of human respiratory cilia.人类呼吸道纤毛的方向。
Eur Respir J. 1988 Mar;1(3):257-61.
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[How useful is the ultrastructural study of the cilia of the respiratory tract in the diagnosis of an immotile cilia syndrome?].[呼吸道纤毛超微结构研究在诊断纤毛不动综合征中具有多大作用?]
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Short nasal respiratory cilia and impaired mucociliary function.鼻呼吸纤毛短小,黏液纤毛功能受损。
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