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无牙下颌早期负荷与延迟负荷及即刻负荷情况下种植体丧失和牙槽嵴骨吸收的系统评价与Meta分析

Implant loss and crestal bone loss in early loading versus delayed and immediate loading in edentulous mandibles. A systematic review and meta-analysis.

作者信息

Pardal-Peláez Beatriz, Flores-Fraile Javier, Pardal-Refoyo José-Luis, Montero Javier

机构信息

DDS, PhD. Associate professor. Faculty of Medicine. Dental Clinic. Department of surgery. Alfonso X St. 37007. University of Salamanca. Salamanca. Spain.

MD, PhD. Honorary collaborating professor. Faculty of Medicine. IBSAL (Salamanca Biomedical Research Institute) member. University assistance complex of Salamanca. Salamanca. Spain.

出版信息

J Clin Exp Dent. 2021 Apr 1;13(4):e397-e405. doi: 10.4317/jced.57966. eCollection 2021 Apr.

Abstract

BACKGROUND

Information about the risk of early loss and crestal bone loss of dental implants which have been loaded early is scant if compared with data available for those conventionally or immediately loaded. A meta-analysis of early loss and crestal bone loss in immediate or delayed loaded full mandibular denture retaining dental implants has been recently published. It is interesting to evaluate also the risks of early versus immediate and delayed loading in complete mandibular restorations. The purpose of this systematic review and meta-analysis was to study early (EL) versus immediate (IL) and delayed loading (DL) protocols in edentulous mandibles to determine whether differences exist in implant success and crestal bone loss.

MATERIAL AND METHODS

The literature review was conducted in PubMed, Web of Science, and the Cochrane Library. Seven randomized clinical trials were included.

RESULTS

The result of a meta-analysis of implant loss before 1 year in EL versus IL was 0.34 (95% CI: 0.08, 1.52), favoring the EL control group, while the outcome for crestal bone loss at the three-year observation was -0.10 (95% CI: -0.28, 0.09), with a tendency toward reduced bone loss for EL. In the EL versus DL group, the result of the meta-analysis of implant loss before one year was inconclusive, while in the comparison regarding crestal bone loss in the first year of observation, the result was -0.03 (95% CI: -0.08,-0.02) with a tendency to less bone loss in EL.

CONCLUSIONS

The risk of early implant loss in the IL group was higher than in the EL group. The results in terms of early implant loss in EL versus DL are inconclusive. Besides, crestal bone loss is greater in immediately and delayed loaded implants, at 1 and 3 years of observation, compared to those loaded early. Dental implants, early dental implant loading, dental prostheses, implant- supported, alveolar bone loss, meta-analysis.

摘要

背景

与传统加载或即刻加载的牙种植体相比,早期加载的牙种植体早期脱落和牙槽嵴骨吸收风险的相关信息较少。最近发表了一项关于即刻或延迟加载的全下颌义齿固位牙种植体早期脱落和牙槽嵴骨吸收的荟萃分析。评估全下颌修复中早期加载与即刻加载和延迟加载的风险也很有趣。本系统评价和荟萃分析的目的是研究无牙下颌中早期(EL)与即刻(IL)和延迟加载(DL)方案,以确定种植体成功率和牙槽嵴骨吸收是否存在差异。

材料与方法

在PubMed、科学网和Cochrane图书馆进行文献检索。纳入了七项随机临床试验。

结果

EL组与IL组1年内种植体脱落的荟萃分析结果为0.34(95%CI:0.08,1.52),支持EL对照组,而三年观察期牙槽嵴骨吸收的结果为-0.10(95%CI:-0.28,0.09),EL组有骨吸收减少的趋势。在EL组与DL组中,1年内种植体脱落的荟萃分析结果尚无定论,而在观察第一年牙槽嵴骨吸收的比较中,结果为-0.03(95%CI:-0.08,-0.02),EL组有骨吸收较少的趋势。

结论

IL组早期种植体脱落的风险高于EL组。EL组与DL组早期种植体脱落的结果尚无定论。此外,与早期加载的种植体相比,即刻和延迟加载的种植体在1年和3年观察期时牙槽嵴骨吸收更多。牙种植体、早期牙种植体加载、牙修复体、种植体支持、牙槽骨吸收、荟萃分析。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d71c/8020311/31003f885c2d/jced-13-e397-g001.jpg

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