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血管周细胞瘤(AFH)不寻常的临床表现及独特的影像学表现。

Angiomatoid fibrous histiocytoma (AFH) unusual clinical presentation and unique radiological findings.

作者信息

Khader Mohammed, Alyafei Tahiya, Ibrahim Sulafa, Elaiwy Orwa

机构信息

Department of Radiology, Hamad General Hospital, Doha, Qatar.

Department of Pathology, Hamad General Hospital, Doha, Qatar.

出版信息

BJR Case Rep. 2020 Dec 2;7(2):20190069. doi: 10.1259/bjrcr.20190069. eCollection 2021 Apr 1.

DOI:10.1259/bjrcr.20190069
PMID:33841896
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8008459/
Abstract

Angiomatoid fibrous histiocytoma (AFH) are rare soft tissue mesenchymal neoplasms that commonly affect children and young adults. They are classified as "intermediate tumours of uncertain differentiation". We present a case of an 8-year-old child with a left thigh AFH and antecedent history of minor trauma showing perilesional oedema and enhancement at MRI, leading to an initial working diagnosis of infected haematoma that contributed to the challenge in reaching the final diagnosis. Although most of the imaging features of AFH previously described in the literature are demonstrated in this case, the presence of arterial vascular channels within the tumour and feeding branch from the left profunda femoris artery is unusual and to our knowledge the first to be published in the literature.

摘要

血管样纤维组织细胞瘤(AFH)是罕见的软组织间叶性肿瘤,常见于儿童和年轻人。它们被归类为“分化不确定的中间型肿瘤”。我们报告一例8岁儿童,左大腿患有AFH,有轻微外伤史,MRI显示病灶周围水肿及强化,最初的诊断考虑为感染性血肿,这给最终诊断带来了挑战。尽管本例显示了文献中先前描述的AFH的大多数影像学特征,但肿瘤内存在动脉血管通道以及来自左股深动脉的供血分支并不常见,据我们所知,这是首次在文献中发表。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7fc/8008459/dbe0a0ef7cbf/bjrcr.20190069.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7fc/8008459/aefd9ec7426f/bjrcr.20190069.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7fc/8008459/fe03359271ee/bjrcr.20190069.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7fc/8008459/6b5b75012a1d/bjrcr.20190069.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7fc/8008459/a869000ffe9f/bjrcr.20190069.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7fc/8008459/dbe0a0ef7cbf/bjrcr.20190069.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7fc/8008459/aefd9ec7426f/bjrcr.20190069.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7fc/8008459/fe03359271ee/bjrcr.20190069.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7fc/8008459/6b5b75012a1d/bjrcr.20190069.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7fc/8008459/a869000ffe9f/bjrcr.20190069.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7fc/8008459/dbe0a0ef7cbf/bjrcr.20190069.g005.jpg

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Clin Orthop Relat Res. 2017 Sep;475(9):2280-2282. doi: 10.1007/s11999-017-5426-2. Epub 2017 Jun 27.
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Angiomatoid fibrous histiocytoma: a series of seven cases including genetically confirmed aggressive cases and a literature review.血管样纤维组织细胞瘤:7例病例系列,包括基因确诊的侵袭性病例及文献综述
BMC Musculoskelet Disord. 2017 Jan 23;18(1):31. doi: 10.1186/s12891-017-1390-y.
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Angiomatoid fibrous histiocytoma: novel MR imaging findings.
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Skeletal Radiol. 2016 May;45(5):661-70. doi: 10.1007/s00256-016-2344-4. Epub 2016 Feb 27.
4
Imaging of childhood angiomatoid fibrous histiocytoma with pathological correlation.儿童血管样纤维组织细胞瘤的影像学表现及其与病理的相关性
Pediatr Radiol. 2015 Nov;45(12):1796-802. doi: 10.1007/s00247-015-3404-y. Epub 2015 Jul 11.
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