Nguyen Quynh, Vervoort Dominique, Phan Kevin, Luc Jessica G Y
Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
John Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
J Thorac Dis. 2021 Mar;13(3):1833-1850. doi: 10.21037/jtd-20-2682.
Unruptured sinus of Valsalva aneurysms (SVAs) are rare cardiac lesions that arise due to congenital or acquired etiologies. They could be asymptomatic or cause various clinical manifestations as a consequence of their mass effect on the coronary arteries, heart valves, and other adjacent structures. While the factors predicting SVA rupture are not fully understood, ruptured SVAs carry a high complication and mortality rate, highlighting the need for early recognition and management of unruptured SVAs. Imaging modalities such as echocardiography, computed tomography (CT), angiography, and magnetic resonance imaging (MRI) are essential in identifying and characterizing the aneurysm as well as associated cardiac anomalies. However, there are no specific guidelines for the diagnosis and management of SVAs. Herein, we performed a contemporary systematic review to examine the presentation, diagnostic tests and findings, as well as outcomes for surgical intervention of unruptured SVAs. We demonstrate that surgical repair remains the preferred method of treatment in order to prevent complications such as rupture or thrombus formation. Surgery should be prompted in patients with symptomatic, large, or rapidly expanding unruptured SVAs, as well as those unruptured SVAs that contain intraluminal thrombi, have a mass effect on surrounding structures, or are recurrent. Surgical outcomes are generally good with favourable prognosis and minimal recurrence.
未破裂的瓦氏窦瘤(SVA)是一种罕见的心脏病变,由先天性或后天性病因引起。它们可能无症状,也可能因其对冠状动脉、心脏瓣膜和其他相邻结构的占位效应而导致各种临床表现。虽然预测SVA破裂的因素尚未完全明确,但破裂的SVA具有较高的并发症和死亡率,这凸显了早期识别和处理未破裂SVA的必要性。超声心动图、计算机断层扫描(CT)、血管造影和磁共振成像(MRI)等影像学检查对于识别和描述动脉瘤以及相关心脏异常至关重要。然而,目前尚无关于SVA诊断和治疗的具体指南。在此,我们进行了一项当代系统评价,以研究未破裂SVA的表现、诊断检查和结果以及手术干预的结局。我们证明,手术修复仍然是首选的治疗方法,以预防破裂或血栓形成等并发症。对于有症状的、较大的或迅速增大的未破裂SVA患者,以及那些腔内有血栓、对周围结构有占位效应或复发的未破裂SVA患者,应及时进行手术。手术结局一般良好,预后良好,复发率低。