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股骨骨骺滑脱作为潜在代谢紊乱的表现:假性甲状旁腺功能减退症和青少年甲状腺功能减退症。

Slipped Capital Femoral Epiphysis as a Presentation of Underlying Metabolic Disorders: Pseudohypoparathyroidism and Juvenile Hypothyroidism.

作者信息

Zelaya Rainel, Zarka Anthony, Byerly Douglas

机构信息

Radiology, Brooke Army Medical Center, Fort Sam Houston, USA.

Pediatric Radiology, Baylor College of Medicine/Children's Hospital of San Antonio, San Antonio, USA.

出版信息

Cureus. 2021 Mar 9;13(3):e13775. doi: 10.7759/cureus.13775.

DOI:10.7759/cureus.13775
PMID:33842151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8025792/
Abstract

Slipped capital femoral epiphysis (SCFE) is an abnormality of the proximal femoral physis typically occurring in adolescents and most commonly associated with obesity, although its exact etiology is unknown. In addition to obesity, other associations and predisposing factors proposed in the literature include trauma, vascular injury or compromise, and immunologic, genetic, and metabolic conditions. While not common, metabolic conditions are known to predispose to SCFE and it is essential for radiologists to recognize SCFE as a possible initial presentation of an underlying metabolic disorder. Understanding imaging findings and identification of atypical presentations of SCFE by radiologists can assist clinicians in guiding workup and lead to expedited treatment to prevent worsening outcomes associated with developmental delay.

摘要

股骨头骨骺滑脱(SCFE)是一种股骨近端骨骺异常,通常发生于青少年,最常见于肥胖者,但其确切病因尚不清楚。除肥胖外,文献中提出的其他相关因素和易感因素包括创伤、血管损伤或受损以及免疫、遗传和代谢状况。虽然不常见,但已知代谢状况易引发SCFE,放射科医生必须认识到SCFE可能是潜在代谢紊乱的初始表现。放射科医生了解影像学表现并识别SCFE的非典型表现,有助于临床医生指导检查,并加快治疗,以防止与发育迟缓相关的不良后果恶化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6090/8025792/5846bc99db13/cureus-0013-00000013775-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6090/8025792/e5457b7c3601/cureus-0013-00000013775-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6090/8025792/7851d34cae56/cureus-0013-00000013775-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6090/8025792/eb03384e164a/cureus-0013-00000013775-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6090/8025792/0e752ad351ef/cureus-0013-00000013775-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6090/8025792/31ea42b784a2/cureus-0013-00000013775-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6090/8025792/5846bc99db13/cureus-0013-00000013775-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6090/8025792/e5457b7c3601/cureus-0013-00000013775-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6090/8025792/7851d34cae56/cureus-0013-00000013775-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6090/8025792/eb03384e164a/cureus-0013-00000013775-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6090/8025792/0e752ad351ef/cureus-0013-00000013775-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6090/8025792/31ea42b784a2/cureus-0013-00000013775-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6090/8025792/5846bc99db13/cureus-0013-00000013775-i06.jpg

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引用本文的文献

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本文引用的文献

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Diagnosis and management of pseudohypoparathyroidism and related disorders: first international Consensus Statement.假性甲状旁腺功能减退症及相关疾病的诊断与管理:第一份国际共识声明。
Nat Rev Endocrinol. 2018 Aug;14(8):476-500. doi: 10.1038/s41574-018-0042-0.
2
Prepubertal onset of slipped capital femoral epiphysis associated with hypothyroidism: a case report and literature review.与甲状腺功能减退症相关的青春期前发病的股骨头骨骺滑脱:病例报告及文献复习。
BMC Endocr Disord. 2017 Sep 18;17(1):59. doi: 10.1186/s12902-017-0210-6.
3
Pinning the slipped and contralateral hips in the treatment of slipped capital femoral epiphysis.
在治疗股骨头骨骺滑脱时对滑脱侧及对侧髋关节进行固定。
J Child Orthop. 2017 Apr;11(2):110-113. doi: 10.1302/1863-2548-11-170022.
4
Bone age: assessment methods and clinical applications.骨龄:评估方法与临床应用
Clin Pediatr Endocrinol. 2015 Oct;24(4):143-52. doi: 10.1297/cpe.24.143. Epub 2015 Oct 24.
5
Slipped capital femoral epiphysis: how to evaluate with a review and update of treatment.股骨头滑脱:如何评估与治疗的回顾及更新。
Pediatr Clin North Am. 2014 Dec;61(6):1119-35. doi: 10.1016/j.pcl.2014.08.001. Epub 2014 Sep 26.
6
Slipped capital femoral epiphysis and its association with endocrine, metabolic and chronic diseases: a systematic review of the literature.股骨头骨骺滑脱及其与内分泌、代谢和慢性疾病的关联:文献系统综述
J Child Orthop. 2013 Jun;7(3):213-23. doi: 10.1007/s11832-013-0493-8. Epub 2013 Mar 30.
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Skeletal manifestations of juvenile hypothyroidism and the impact of treatment on skeletal system.青少年甲状腺功能减退症的骨骼表现及治疗对骨骼系统的影响。
Indian J Endocrinol Metab. 2013 Oct;17(Suppl 1):S181-3. doi: 10.4103/2230-8210.119565.
8
Pseudohypoparathyroidism as a rare cause of bilateral slipped capital femoral epiphysis.假性甲状旁腺功能减退症作为双侧股骨头骨骺滑脱的罕见病因。
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Clinical practice guidelines for hypothyroidism in adults: cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association.成人甲状腺功能减退症临床实践指南:由美国临床内分泌医师学会和美国甲状腺协会共同赞助。
Endocr Pract. 2012 Nov-Dec;18(6):988-1028. doi: 10.4158/EP12280.GL.
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