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上皮组织再生医学：过去的经验与未来的目标

Regenerative Medicine of Epithelia: Lessons From the Past and Future Goals.

作者信息

Maurizi Eleonora, Adamo Davide, Magrelli Federica Maria, Galaverni Giulia, Attico Eustachio, Merra Alessia, Maffezzoni Maria Benedetta Rizzarda, Losi Lorena, Genna Vincenzo Giuseppe, Sceberras Virginia, Pellegrini Graziella

机构信息

Holostem Terapie Avanzate S.r.l., Modena, Italy.

Interdepartmental Centre for Regenerative Medicine "Stefano Ferrari", University of Modena and Reggio Emilia, Modena, Italy.

出版信息

Front Bioeng Biotechnol. 2021 Mar 25;9:652214. doi: 10.3389/fbioe.2021.652214. eCollection 2021.

DOI:10.3389/fbioe.2021.652214
PMID:33842447
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8026866/
Abstract

This article explores examples of successful and unsuccessful regenerative medicine on human epithelia. To evaluate the applications of the first regenerated tissues, the analysis of the past successes and failures addresses some pending issues and lay the groundwork for developing new therapies. Research should still be encouraged to fill the gap between pathologies, clinical applications and what regenerative medicine can attain with current knowledge.

摘要

本文探讨了人类上皮组织再生医学成功与失败的案例。为评估首批再生组织的应用情况，对过去的成功与失败进行分析，解决了一些悬而未决的问题，并为开发新疗法奠定了基础。仍应鼓励开展研究，以填补病理学、临床应用与再生医学利用现有知识所能达到的水平之间的差距。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1244/8026866/cf572bd81f7d/fbioe-09-652214-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1244/8026866/730f228b9a0a/fbioe-09-652214-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1244/8026866/cf572bd81f7d/fbioe-09-652214-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1244/8026866/730f228b9a0a/fbioe-09-652214-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1244/8026866/cf572bd81f7d/fbioe-09-652214-g002.jpg

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Sci Rep. 2020 Nov 13;10(1):19817. doi: 10.1038/s41598-020-76882-w.
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Cells. 2024 Sep 10;13(18):1514. doi: 10.3390/cells13181514.
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Extracellular Vesicles Isolated from Equine Adipose-Derived Stromal Stem Cells (ASCs) Mitigate Tunicamycin-Induced ER Stress in Equine Corneal Stromal Stem Cells (CSSCs).从马脂肪来源的间充质干细胞（ASCs）中分离出的细胞外囊泡可减轻衣霉素诱导的马角膜基质干细胞（CSSCs）的内质网应激。
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