Pavlova Milena K, Ng Marcus, Allen Rebecca M, Boly Melanie, Kothare Sanjeev, Zaveri Hiten, Zee Phyllis C, Adler Gail, Buchanan Gordon F, Quigg Mark S
Department of Neurology, 1861Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
12359Department of Internal Medicine, University of Manitoba, Winnipeg, Canada.
Epilepsy Curr. 2021 Apr 12;21(3):15357597211004549. doi: 10.1177/15357597211004549.
Epilepsy is a chronic disease with multiple, complex comorbidities. Bidirectional relationships exist among seizures, sleep, circadian rhythms, and diseases within and outside of the central nervous system. Seizures fragment sleep and can contribute to development of sleep disorders, which in turn leads to worse overall health and more seizures. Moreover, treatment options are often limited by interactions with anti-seizure medications. Advances in the fields of epilepsy and in sleep medicine have been made separately, and therefore treating patients with these comorbidities necessitates interdisciplinary approach. The focus of this section of the Sleep and Epilepsy Workgroup was to identify methods of collaboration and outline investigational, educational, and treatment priorities to mutually advance what we consider a combined field.
癫痫是一种伴有多种复杂合并症的慢性疾病。癫痫发作、睡眠、昼夜节律以及中枢神经系统内外的疾病之间存在双向关系。癫痫发作会破坏睡眠，并可能导致睡眠障碍的发生，而睡眠障碍反过来又会导致整体健康状况恶化和癫痫发作增多。此外，治疗选择往往受到与抗癫痫药物相互作用的限制。癫痫领域和睡眠医学领域各自都取得了进展，因此，治疗患有这些合并症的患者需要采用跨学科方法。睡眠与癫痫工作组这一部分的重点是确定合作方法，并概述研究、教育和治疗重点，以共同推动我们所认为的这个联合领域的发展。
