Department of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Department of Physiology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Int J Neurosci. 2023 Mar;133(3):248-256. doi: 10.1080/00207454.2021.1909011. Epub 2021 Apr 14.
Psychiatric comorbidity is common among migraineurs, such as anxiety and depression. This type of comorbidity contributed to migraine chronicity, management efficacy, and increasing the risk for other comorbidities. This study designed to estimate the prevalence of depression, anxiety, and stress (DAS) symptoms among Saudi migraine patients using the validated instrument (DASS-21) and considering socio-demographic factors and individual differences that affect migraine progression and prognosis. Cross-sectional, self-administered, web-based-questionnaire distributed among Saudi Arabia general population. Only migraine patients with clinical diagnosis allowed to complete the survey. A total of 247 migraine patients participated and they are predominantly females, with ages between 16 and 45 years, Saudi nationals, married, non-smokers but do not exercise regularly. About 73.3% met the abnormal score in anxiety on DASS-21, as well as 70.9% in depression and 72.3% in stress. Four statistically significant correlations with DAS were identified. Migraine patients who are smoking have a higher prevalence of depression and stress ( < 0.05). Those who do not exercise regularly have a higher prevalence only for depression ( = 0.03). A higher prevalence of all emotional states was found in patients with more than one co-morbidity and patients with a clinical diagnosis of depression and anxiety disorders ( < 0.02). The sensitivity of DASS-21 for depression and anxiety are 96.9% and 93.3%, respectively. Both smoking cessation and exercise to prevent migraine attacks deserve a clinical trial. A holistic approach is needed to decrease psychiatry-related disability and promote management outcomes in migraineurs. Using DASS-21 for migraine patients as a routine screening instrument is valuable to prevent psychiatric comorbidity.
精神共病在偏头痛患者中很常见，例如焦虑和抑郁。这种共病导致偏头痛的慢性化、管理效果降低，并增加了其他共病的风险。本研究旨在使用经过验证的工具（DASS-21）评估沙特偏头痛患者的抑郁、焦虑和压力（DAS）症状的患病率，并考虑影响偏头痛进展和预后的社会人口因素和个体差异。横断面、自我管理、基于网络的问卷分发给沙特阿拉伯的一般人群。只有有临床诊断的偏头痛患者才能完成调查。共有 247 名偏头痛患者参与，他们主要是女性，年龄在 16 至 45 岁之间，沙特国民，已婚，不吸烟但不经常锻炼。约 73.3%的患者在 DASS-21 中出现焦虑异常评分，70.9%的患者出现抑郁异常评分，72.3%的患者出现压力异常评分。确定了四个与 DAS 具有统计学意义的相关性。吸烟的偏头痛患者抑郁和压力的患病率更高（ < 0.05）。不经常锻炼的患者仅在抑郁方面的患病率更高（ = 0.03）。在有多种共病和有临床诊断的抑郁和焦虑障碍的患者中，发现所有情绪状态的患病率更高（ < 0.02）。DASS-21 对抑郁和焦虑的敏感性分别为 96.9%和 93.3%。戒烟和锻炼以预防偏头痛发作都值得进行临床试验。需要采取整体方法来减少与精神病学相关的残疾并改善偏头痛患者的管理效果。在偏头痛患者中使用 DASS-21 作为常规筛查工具对于预防精神共病很有价值。
