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新型冠状病毒肺炎疫情影响人群创伤后应激症状的患病率:一项荟萃分析。

Prevalence of post-traumatic stress symptoms among people influenced by coronavirus disease 2019 outbreak: A meta-analysis.

机构信息

Department of Social Medicine and Health Management, Xiangya School of Public Health, Central South University, Changsha, Hunan, China.

Mental Health Institute, Second Xian gya Hospital, Central South University, Changsha, Hunan, China.

出版信息

Eur Psychiatry. 2021 Apr 12;64(1):e30. doi: 10.1192/j.eurpsy.2021.24.

Abstract

BACKGROUND

As one of the most widely researched consequence of traumatic events, the prevalence of post-traumatic stress symptoms among people exposed to the trauma resulting from coronavirus disease 2019 (COVID-19) outbreak varies greatly across studies. This review aimed at examining the pooled prevalence of post-traumatic stress symptoms among people exposed to the trauma resulting from COVID-19 outbreak.

METHODS

Systematic searches of databases were conducted for literature published on PubMed, EMBASE, Web of Science, the Cochrane Library, PsycArticle, and Chinese National Knowledge Infrastructure until October 14, 2020. Statistical analyses were performed using R software (PROSPERO registration number: CRD42020180309).

RESULTS

A total of 106,713 people exposed to the trauma resulting from the COVID-19 outbreak were identified in the 76 articles, of which 33,810 were reported with post-traumatic stress symptoms. The pooled prevalence of post-traumatic stress symptoms among people exposed to the trauma resulting from COVID-19 outbreak was 28.34%, with a 95% confidence interval of 23.03-34.32%. Subgroup analysis indicated that older age, male and bigger sample size were associated with higher prevalence of post-traumatic stress symptoms. After controlling for other factors, the results of meta-regression showed that the influence of gender and sample size on prevalence is no longer significant.

CONCLUSIONS

Symptoms of post-traumatic stress disorder (PTSD) were very common among people exposed to the trauma resulting from COVID-19 outbreak. Further research is needed to explore more possible risk factors for post-traumatic stress symptoms and identify effective strategies for preventing PTSD-related symptoms among people exposed to the trauma resulting from COVID-19 outbreak.

摘要

背景

作为创伤事件最广泛研究的后果之一,暴露于新型冠状病毒病 2019(COVID-19)爆发所造成创伤的人群中创伤后应激症状的流行率在不同研究中差异很大。本综述旨在检查暴露于 COVID-19 爆发所造成创伤的人群中创伤后应激症状的总患病率。

方法

对发表于 PubMed、EMBASE、Web of Science、Cochrane Library、PsycArticle 和中国国家知识基础设施数据库的文献进行系统检索,检索时间截至 2020 年 10 月 14 日。使用 R 软件(PROSPERO 注册号:CRD42020180309)进行统计分析。

结果

在 76 篇文章中确定了 106713 名暴露于 COVID-19 爆发所造成创伤的人群,其中 33810 人报告有创伤后应激症状。暴露于 COVID-19 爆发所造成创伤的人群中创伤后应激症状的总患病率为 28.34%,95%置信区间为 23.03%-34.32%。亚组分析表明,年龄较大、男性和较大的样本量与较高的创伤后应激症状患病率相关。在控制其他因素后,元回归分析的结果表明,性别和样本量对患病率的影响不再显著。

结论

暴露于 COVID-19 爆发所造成创伤的人群中,创伤后应激障碍(PTSD)症状非常常见。需要进一步研究以探索 PTSD 症状的更多可能风险因素,并确定预防 COVID-19 爆发所造成创伤的人群中 PTSD 相关症状的有效策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eff1/8060540/0cbe9981eebb/S0924933821000249_fig1.jpg

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