Wei Wen-Bo, Dang Sha-Jie, Wei Ling, Liu Tian, Wang Jue
The Key Laboratory of Biomedical Information Engineering of Ministry of Education, The Key Laboratory of Neuro-informatics & Rehabilitation Engineering of Ministry of Civil Affairs, and Institute of Health and Rehabilitation Science, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, P. R. China.
National Engineering Research Center of Health Care and Medical Devices, Guangzhou, China.
BMC Musculoskelet Disord. 2021 Apr 12;22(1):347. doi: 10.1186/s12891-021-04209-5.
To assess the therapeutic efficacy of transforaminal epidural steroid injection (TFESI) combined with radio frequency (RF) for the treatment of lumbar disc herniation (LDH).
A total of 230 patients participated in the study: TFESI (Group T, n = 110), TFESI combined with RF (Group TR, n = 120). Visual analogue scale (VAS), Oswestry disability index (ODI) and Global perceived effect (GPE) scale were measured pre-operation, 1, 3, 6, 12 and 24 months after the operation. Hospitalization time, treatment time, complications, and recurrence were compared between the two groups.
The VAS and ODI at each observation point of the post-operation were significantly decreased compared with the pre-operation in both groups (P < 0.05). There was no statistically difference of VAS and ODI between the two groups at 1 and 3 months of the post-operation (P > 0.05). However, The VAS and ODI scores in Group TR were significantly lower than that in Group T at 6, 12 and 24 months of the post-operation (P < 0.05). The GPE in group TR was high in the early days, while that at 1 and 3 months after treatment was significantly higher than that in group T (P < 0.05). The recurrence rate in Group TR was lower than that in Group T (P = 0.002). There was no significant difference in hospitalization time, complications, VAS and ODI score at the pre-operation between the two groups (P > 0.05).
These findings suggest that TFESI combined with RF could effectively improve the pain and function, and had a long-term satisfactory effect for the treatment of LDH.
评估经椎间孔硬膜外类固醇注射（TFESI）联合射频（RF）治疗腰椎间盘突出症（LDH）的疗效。
共有230例患者参与研究：TFESI组（T组，n = 110），TFESI联合RF组（TR组，n = 120）。在术前、术后1、3、6、12和24个月测量视觉模拟量表（VAS）、Oswestry功能障碍指数（ODI）和整体疗效（GPE）量表。比较两组的住院时间、治疗时间、并发症及复发情况。
两组术后各观察点的VAS和ODI均较术前显著降低（P < 0.05）。术后1个月和3个月时，两组的VAS和ODI无统计学差异（P > 0.05）。然而，术后6个月、12个月和24个月时，TR组的VAS和ODI评分显著低于T组（P < 0.05）。TR组早期GPE较高，治疗后1个月和3个月时显著高于T组（P < 0.05）。TR组的复发率低于T组（P = 0.002）。两组术前的住院时间、并发症、VAS和ODI评分无显著差异（P > 0.05）。
这些结果表明，TFESI联合RF可有效改善疼痛和功能，对LDH的治疗具有长期满意的效果。
