Suppr超能文献

印度尼西亚雅加达 COVID-19 根除计划中早期检测和疫苗接种策略的影响。

Impact of early detection and vaccination strategy in COVID-19 eradication program in Jakarta, Indonesia.

机构信息

Department of Mathematics, Universitas Indonesia, Depok, Indonesia.

Department of Mathematics, University of Raparin, Ranya, Kurdistan Region, Iraq.

出版信息

BMC Res Notes. 2021 Apr 12;14(1):132. doi: 10.1186/s13104-021-05540-9.

Abstract

OBJECTIVE

Several essential factors have played a crucial role in the spreading mechanism of COVID-19 (Coronavirus disease 2019) in the human population. These factors include undetected cases, asymptomatic cases, and several non-pharmaceutical interventions. Because of the rapid spread of COVID-19 worldwide, understanding the significance of these factors is crucial in determining whether COVID-19 will be eradicated or persist in the population. Hence, in this study, we establish a new mathematical model to predict the spread of COVID-19 considering mentioned factors.

RESULTS

Infection detection and vaccination have the potential to eradicate COVID-19 from Jakarta. From the sensitivity analysis, we find that rapid testing is crucial in reducing the basic reproduction number when COVID-19 is endemic in the population rather than contact trace. Furthermore, our results indicate that a vaccination strategy has the potential to relax social distancing rules, while maintaining the basic reproduction number at the minimum possible, and also eradicate COVID-19 from the population with a higher vaccination rate. In conclusion, our model proposed a mathematical model that can be used by Jakarta's government to relax social distancing policy by relying on future COVID-19 vaccine potential.

摘要

目的

在人类群体中,COVID-19(2019 年冠状病毒病)传播机制中涉及了几个重要因素。这些因素包括未被发现的病例、无症状病例以及多种非药物干预措施。由于 COVID-19 在全球范围内的迅速传播,了解这些因素的重要性对于确定 COVID-19 是否会被消灭或在人群中持续存在至关重要。因此,在本研究中,我们建立了一个新的数学模型,以考虑到上述因素来预测 COVID-19 的传播。

结果

感染检测和疫苗接种有潜力在雅加达消除 COVID-19。从敏感性分析中,我们发现,当 COVID-19 在人群中流行时,快速检测比接触追踪更能降低基本繁殖数。此外,我们的结果表明,接种疫苗策略具有缓解社交距离规则的潜力,同时将基本繁殖数保持在尽可能低的水平,并在较高的疫苗接种率下从人群中消除 COVID-19。总之,我们的模型提出了一种数学模型,雅加达政府可以依靠未来 COVID-19 疫苗的潜力来放松社交距离政策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f0/8042888/b78620afb587/13104_2021_5540_Fig1_HTML.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验