Department of Pulmonary Medicine, CHU Saint-Pierre, Brussels, Belgium.
Université Libre de Bruxelles (ULB), Brussels, Belgium.
Sleep Breath. 2022 Mar;26(1):125-132. doi: 10.1007/s11325-021-02367-3. Epub 2021 Apr 13.
Telemonitoring (TMg) for patients treated with continuous positive airway pressure (CPAP) is now routine care in some sleep labs. The purpose of the present study was to identify technical interventions associated with improved CPAP compliance in a real-life cohort of newly telemonitored patients with obstructive sleep apnea (OSA) during the first 6 months of treatment.
All patients with moderate-to-severe OSA (apnea-hypopnea index (AHI) ≥ 15/h) who were newly treated with CPAP were included in the study and telemonitored. A group educational session was scheduled after 1 month. Technical interventions were performed at the patient's request and during scheduled visits and the impact of each intervention on CPAP therapy compliance was collected.
Between May 2018 and Dec 2019, 349 patients newly diagnosed with OSA were hospitalized in the sleep lab for CPAP titration and 212 patients were included (mean age 54.6 ± 13.1 years, mean BMI 31.7 ± 5.8 kg/m, mean AHI 42.8 ± 22.0). TMg acceptance rate was 87%. Mean 6-month compliance was 275 ± 154 min, 13% stopped CPAP, and 17% were non-compliant. Correlations were observed between BMI (r = 0.15, p = 0.029), median and 95th percentile leaks (r = -0.23 and -0.18, p = 0.016 and 0.002), and CPAP compliance. During follow-up, 92 interventions were required, mainly for mask change (n = 80). Pressure modification (n = 16) was the only intervention that increased CPAP use > 30 min/night, p = 0.021.
Pressure modification was the only adaptation that significantly increased CPAP compliance during the first 6 months. Remote TMg allows providing daily, accurate, and immediate feedback that could help clinicians to confirm that the CPAP treatment is effective.
在一些睡眠实验室中,对接受持续气道正压通气(CPAP)治疗的患者进行远程监测(TMg)已成为常规护理。本研究的目的是在接受 CPAP 治疗的新远程监测的阻塞性睡眠呼吸暂停(OSA)患者的首个 6 个月中,确定与技术干预相关的、可提高 CPAP 顺应性的因素。
所有中重度 OSA(呼吸暂停低通气指数(AHI)≥15/h)患者均纳入研究并接受远程监测。在 1 个月后安排了一次小组教育课程。根据患者的要求并在预约时进行技术干预,并收集每次干预对 CPAP 治疗顺应性的影响。
2018 年 5 月至 2019 年 12 月,349 例新诊断为 OSA 的患者因 CPAP 滴定而住院于睡眠实验室,其中 212 例患者被纳入研究(平均年龄 54.6±13.1 岁,平均 BMI 31.7±5.8kg/m,平均 AHI 42.8±22.0)。TMg 接受率为 87%。平均 6 个月的顺应性为 275±154min,13%的患者停止 CPAP 治疗,17%的患者不依从。BMI(r=0.15,p=0.029)、中值和 95%分位数泄漏(r=-0.23 和-0.18,p=0.016 和 0.002)与 CPAP 顺应性之间存在相关性。在随访期间,需要进行 92 次干预,主要是更换面罩(n=80)。压力调整(n=16)是唯一增加 CPAP 使用时间>30min/晚的干预措施,p=0.021。
压力调整是首个 6 个月内显著提高 CPAP 顺应性的唯一方法。远程 TMg 可以提供每日、准确和即时的反馈,这有助于临床医生确认 CPAP 治疗是否有效。