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在一项戒烟随机对照试验中,纳入的酒精和其他药物使用者使用尼古丁替代疗法的模式和预测因素。

Patterns and predictors of nicotine replacement therapy use among alcohol and other drug clients enrolled in a smoking cessation randomised controlled trial.

机构信息

The University of Newcastle, Callaghan, Australia.

The University of Newcastle, Callaghan, Australia.

出版信息

Addict Behav. 2021 Aug;119:106935. doi: 10.1016/j.addbeh.2021.106935. Epub 2021 Mar 29.

Abstract

INTRODUCTION

Nicotine replacement therapy (NRT) use to support client smoking quit attempts is low and inconsistent at alcohol and other drug (AOD) treatment services. This study examined predictors of any NRT use and combination NRT use among AOD clients who were smokers.

METHODS

The study was part of a cluster-RCT of an organisational change intervention to introduce smoking cessation support as part of routine treatment in 32 AOD services. The intervention provided AOD services with free NRT and training. Service clients completed baseline (n = 896), 8-week (n = 471) and 6.5-month (n = 427) follow-up surveys. Mixed-model logistic regression examined whether baseline socio-demographic and smoking variables were associated with single and combination NRT use.

RESULTS

At 8-weeks follow-up 57% (n = 269/471), and at 6.5-months 33% (n = 143/427) of participants reported using at least one form of NRT. Odds of NRT use at 8-weeks follow-up were greater among participants from treatment vs control group (OR = 3.69, 95%CI 1.8-7.4; p < 0.001), higher vs lower nicotine dependence (OR = 1.74 95%CI 1.1-2.8; p = 0.024), or those motivated to quit (OR = 1.18 95%CI 1.0-1.4; p = 0.017). At 6.5-months, only the treatment arm remained significant. Combination NRT use at the 8-week follow-up was higher among those in treatment vs control group (OR = 2.75 95%CI 1.4-5.6; p = 0.005), or with higher vs lower nicotine dependence (OR = 2.12 95%CI 1.2-3.8; p = 0.014). No factors were associated with combination NRT use at 6.5-months.

CONCLUSIONS

An organisational change intervention that supplied AOD services with NRT training and products to provide to clients during treatment significantly increases client single form and combination NRT use in the short term.

摘要

引言

尼古丁替代疗法(NRT)在酒精和其他药物(AOD)治疗服务中用于支持客户戒烟尝试的使用率较低且不一致。本研究调查了在吸烟者 AOD 患者中,任何 NRT 使用和联合 NRT 使用的预测因素。

方法

该研究是一项组织变革干预的集群 RCT 的一部分,该干预旨在将戒烟支持作为 32 个 AOD 服务中常规治疗的一部分。该干预为 AOD 服务提供了免费的 NRT 和培训。服务客户在基线(n=896)、8 周(n=471)和 6.5 个月(n=427)时完成了随访调查。混合模型逻辑回归检验了基线社会人口统计学和吸烟变量是否与单一和联合 NRT 使用相关。

结果

在 8 周的随访中,57%(n=269/471),在 6.5 个月时,33%(n=143/427)的参与者报告至少使用了一种形式的 NRT。在 8 周随访时,与对照组相比,来自治疗组的参与者使用 NRT 的可能性更高(OR=3.69,95%CI 1.8-7.4;p<0.001),尼古丁依赖程度更高(OR=1.74 95%CI 1.1-2.8;p=0.024)或更有戒烟意愿(OR=1.18 95%CI 1.0-1.4;p=0.017)。在 6.5 个月时,只有治疗组仍然具有统计学意义。在 8 周的随访中,与对照组相比,联合使用 NRT 的可能性更高(OR=2.75 95%CI 1.4-5.6;p=0.005),或尼古丁依赖程度更高(OR=2.12 95%CI 1.2-3.8;p=0.014)。在 6.5 个月时,没有任何因素与联合使用 NRT 相关。

结论

一项组织变革干预措施,为 AOD 服务提供 NRT 培训和产品,供客户在治疗期间使用,这显著增加了客户在短期内单一形式和联合 NRT 的使用。

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