Brook I
Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814.
J Clin Microbiol. 1988 Jun;26(6):1181-8. doi: 10.1128/jcm.26.6.1181-1188.1988.
Examination of 15,844 clinical specimens submitted over 12 years (1973 to 1985) to the anaerobic microbiology laboratories in two military hospitals demonstrated the recovery of anaerobic bacteria in 4,458 (28.1%) specimens. The specimens yielded 6,557 anaerobic isolates (1.47 isolates per specimen). Bacteroides spp. accounted for 43% of all isolates; anaerobic gram-positive cocci, 26%; Clostridium spp., 7%; and Fusobacterium spp., 4%. Bacteroides spp. predominated in abscesses, obstetrical and gynecological (OBG) infections, abdominal infections, cysts, wounds, and tumors. Members of the Bacteroides fragilis group accounted for 44% of all Bacteroides spp., and of them, B. fragilis was mostly isolated in abscesses, wounds, abdomen, and blood. Pigmented Bacteroides spp. accounted for 21% of all Bacteroides sp. isolates and were mostly isolated in sinus, eye, chest, bone, and ear infections. Bacteroides melaninogenicus accounted for 42% of this group's isolates. Bacteroides bivius accounted for 9% of Bacteroides spp., and most isolates were found in OBG infections. Anaerobic gram-positive cocci were mostly isolated in OBG infections, abscesses, and wounds. The predominant anaerobic gram-positive cocci were Peptostreptococcus magnus (18%), Peptostreptococcus asaccharolyticus (17%), Peptostreptococcus anaerobius (16%), and Peptostreptococcus prevotii (13%). Clostridium spp. were mostly isolated from wounds, abscesses, abdominal infections, and blood. The predominant strain was Clostridium perfringens (48%). Fusobacterium spp. were recovered in abscesses and abdominal and OBG infections. The predominant isolate was Fusobacterium nucleatum (47%). These data illustrate the relative frequency of the different anaerobic bacteria in a variety of infections and demonstrate the predominance of certain isolates at different sites.
在12年（1973年至1985年）期间，对两家军队医院的厌氧微生物实验室提交的15844份临床标本进行检查，结果显示在4458份（28.1%）标本中分离出厌氧细菌。这些标本共分离出6557株厌氧菌株（每份标本1.47株）。拟杆菌属占所有分离菌株的43%；厌氧革兰氏阳性球菌占26%；梭菌属占7%；梭杆菌属占4%。拟杆菌属在脓肿、妇产科（OBG）感染、腹部感染、囊肿、伤口和肿瘤中占主导地位。脆弱拟杆菌群成员占所有拟杆菌属的44%，其中，脆弱拟杆菌大多在脓肿、伤口、腹部和血液中分离得到。产色素拟杆菌属占所有拟杆菌属分离株的21%，大多在鼻窦、眼睛、胸部、骨骼和耳部感染中分离得到。产黑素拟杆菌占该组分离株的42%。二路拟杆菌占拟杆菌属的9%，大多数分离株见于妇产科感染。厌氧革兰氏阳性球菌大多在妇产科感染、脓肿和伤口中分离得到。主要的厌氧革兰氏阳性球菌是大消化链球菌（18%）、不解糖消化链球菌（17%）、厌氧消化链球菌（16%）和普氏消化链球菌（13%）。梭菌属大多从伤口、脓肿、腹部感染和血液中分离得到。主要菌株是产气荚膜梭菌（48%）。梭杆菌属在脓肿、腹部和妇产科感染中分离得到。主要分离株是具核梭杆菌（47%）。这些数据说明了不同厌氧细菌在各种感染中的相对频率，并证明了某些分离株在不同部位的优势。
