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青霉素G与新型β-内酰胺类抗生素对拟杆菌属临床分离株的活性比较。

Comparison of the activities of penicillin G and new beta-lactam antibiotics against clinical isolates of Bacteroides species.

作者信息

Aldridge K E, Sanders C V, Janney A, Faro S, Marier R L

出版信息

Antimicrob Agents Chemother. 1984 Sep;26(3):410-3. doi: 10.1128/AAC.26.3.410.

Abstract

MICs were determined for 218 clinical isolates of Bacteroides by a broth microdilution method. Imipenem was the most active antibiotic tested. Azlocillin, mezlocillin, and cefoxitin had comparable activities, with resistance among members of the B. fragilis group and B. capillosus. Ceftizoxime was the most active cephalosporin tested. Members of the B. fragilis group showed high levels of resistance to cefotetan and ceftazidime. Resistance to penicillin G varied from 0 to 14%.

摘要

采用肉汤微量稀释法对218株拟杆菌临床分离株进行了最低抑菌浓度(MIC)测定。亚胺培南是所测试的最具活性的抗生素。阿洛西林、美洛西林和头孢西丁具有相当的活性,脆弱拟杆菌群和毛细拟杆菌成员存在耐药情况。头孢唑肟是所测试的最具活性的头孢菌素。脆弱拟杆菌群成员对头孢替坦和头孢他啶表现出高度耐药。对青霉素G的耐药率在0%至14%之间。

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