Department of Pathology, AIIMS, Mangalagiri, Guntur, A.P., India, 522503.
Department of General Surgery, AIIMS, Mangalagiri, Guntur, A.P., India, 522503.
Eur J Med Res. 2021 Apr 13;26(1):34. doi: 10.1186/s40001-021-00505-x.
Rosai-Dorfman-Destombes (RDD) is also known as sinus histiocytosis with massive lymphadenopathy (SHML). It is a benign proliferative disorder of histiocytes, affecting lymph nodes, rarely with extra-nodal involvement. Rapid on-site evaluation (ROSE) with fine-needle aspiration cytology (FNAC) can be utilized as a minimally invasive investigation to avoid unnecessary surgery of this self-limiting disease.
A 65-year-old female presented with complaints of bilateral cervical lymphadenopathy since 1 year. Rapid on-site stain with FNAC from bilateral cervical lymph nodes revealed features of Rosai-Dorfman-Destombes (RDD) disease.
FNAC with rapid on-site evaluation can provide a simple and cost-effective method for looking at the unique cytological features of the disease and act as a first-line investigation.
Rosai-Dorfman-Destombes(RDD)也称为伴有巨大淋巴结病的窦组织细胞增生症(SHML)。它是一种良性组织细胞增生性疾病,影响淋巴结,很少累及淋巴结外。细针穿刺细胞学(FNAC)的现场快速评估(ROSE)可作为一种微创检查方法,避免对这种自限性疾病进行不必要的手术。
一名 65 岁女性因双侧颈部淋巴结肿大 1 年就诊。双侧颈部淋巴结 FNAC 的现场快速染色显示 Rosai-Dorfman-Destombes(RDD)疾病的特征。
FNAC 联合现场快速评估可为观察疾病独特的细胞学特征提供一种简单、经济有效的方法,并可作为一线检查。