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鼻石症,一种罕见病症:31例病例分析及文献综述

Rhinolithiasis, a rare entity: Analysis of 31 cases and literature review.

作者信息

Seyhun Nurullah, Toprak Ebubekir, Kaya Kerem Sami, Dizdar Senem Kurt, Turgut Suat

机构信息

Department of Ear Nose Throat Head and Neck Surgery, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.

出版信息

North Clin Istanb. 2020 Oct 26;8(2):172-177. doi: 10.14744/nci.2020.32391. eCollection 2021.

DOI:10.14744/nci.2020.32391
PMID:33851082
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8039103/
Abstract

OBJECTIVE

Rhinolithiasis is a rare condition which results from deposition of salt around a endogenous or exogenous nidus. In the literature, most of the reports are single case studies. In this study, we aimed to present the characteristics, symptoms, diagnosis, and treatment methods of 31 rhinolithiasis cases and to focus on the current literature.

METHODS

We retrospectively reviewed 31 rhinolithiasis cases which have been diagnosed and treated in a tertiary care center between January 2014 and December 2018. Patient characteristics, presenting symptoms, concomitant sinonasal disorders, and type of surgery were noted. Descriptive statistics were carried out.

RESULTS

Mean age was 25.4±15.7. The cases were comprised 14 female patients (45.2%) and 17 male patients (54.8%). The most common presenting symptom was nasal obstruction (71%). Malodorous unilateral rhinorrhea was present in 17 patients (54.8%). Epistaxis snoring and sleep apnea were other rare symptoms. In 21 of the cases (67.7%), rhinolith was located between inferior turbinate and septum which was the most common location seen in our series. The number of patients who were under the age of 18 was 13, in 2 of them, rhinolith was found to be formed around a plastic bead, and in 2 of them, fruit seeds were the nidus. The most common concomitant sinonasal pathology was septal deviation which was detected in 20 of the patients (64.5%), adenoid vegetation and nasal polyposis were other disorders. In 20 of the patients (64.5%), simple removal of the rhinolith using a forceps with the help of a rigid nasal endoscope was performed. Eight of the 17 patients had severe deviation and septoplasty was performed at the same time, which was the most common concomitant surgical intervention (25.8%). In 3 patients (9.6%), functional endoscopic sinus surgery was performed at the same time.

CONCLUSION

Our series is one of the largest series in the literature. The most common presenting symptom was nasal obstruction followed by malodorous rhinorrhea. Accompanying sinonasal disorders should be addressed to improve the outcome. Rigid or flexible endoscopic examination should be used to detect a rhinolith. Computed tomography scan can diagnose a hidden rhinolith in a patient with nasal obstruction.

摘要

目的

鼻石症是一种罕见疾病,由盐类在体内或外源性病灶周围沉积所致。在文献中,大多数报道为单病例研究。本研究旨在呈现31例鼻石症病例的特征、症状、诊断及治疗方法,并聚焦当前文献。

方法

我们回顾性分析了2014年1月至2018年12月在一家三级医疗中心诊断并治疗的31例鼻石症病例。记录患者特征、出现的症状、伴发的鼻窦疾病及手术类型。进行描述性统计。

结果

平均年龄为25.4±15.7岁。病例包括14例女性患者(45.2%)和17例男性患者(54.8%)。最常见的症状是鼻塞(71%)。17例患者(54.8%)出现单侧恶臭性鼻漏。鼻出血、打鼾和睡眠呼吸暂停是其他罕见症状。21例病例(67.7%)中,鼻石位于下鼻甲与鼻中隔之间,这是我们系列中最常见的位置。18岁以下患者有13例,其中2例鼻石围绕塑料珠形成,2例以果核为病灶。最常见的伴发鼻窦病变是鼻中隔偏曲,20例患者(64.5%)检测到该病变,腺样体增生和鼻息肉是其他疾病。20例患者(64.5%)在硬性鼻内镜辅助下用镊子简单取出鼻石。17例患者中有8例有严重偏曲,同时行鼻中隔成形术,这是最常见的伴发手术干预(25.8%)。3例患者(9.6%)同时行功能性鼻内镜鼻窦手术。

结论

我们的系列是文献中最大的系列之一。最常见的症状是鼻塞,其次是恶臭性鼻漏。应处理伴发的鼻窦疾病以改善预后。应使用硬性或软性内镜检查来发现鼻石。计算机断层扫描可诊断鼻塞患者隐匿性鼻石。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03ee/8039103/0434f918a80b/NCI-8-172-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03ee/8039103/0c72c24e0f6d/NCI-8-172-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03ee/8039103/0434f918a80b/NCI-8-172-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03ee/8039103/0c72c24e0f6d/NCI-8-172-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03ee/8039103/0434f918a80b/NCI-8-172-g002.jpg

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3
Chronic sinusitis-associated antrolith.慢性鼻窦炎相关上颌窦结石
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4
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Clin Case Rep. 2024 Mar 19;12(3):e8679. doi: 10.1002/ccr3.8679. eCollection 2024 Mar.
6
A case report of chronic dacryocystitis caused by nasal stones.鼻腔结石导致慢性泪囊炎 1 例报告。
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7
Rhinolithiasis misdiagnosed as intranasal osteoma: Diagnostic challenges in the telehealth era.误诊为鼻内骨瘤的鼻石症:远程医疗时代的诊断挑战
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IDCases. 2018 Nov 3;14:e00467. doi: 10.1016/j.idcr.2018.e00467. eCollection 2018.
4
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5
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