Section of Neurocritical Care, Rush University Medical Center, Chicago, Illinois.
Department of Neurology, Northwestern Memorial Hospital, Chicago, Illinois.
Semin Neurol. 2021 Aug;41(4):453-462. doi: 10.1055/s-0041-1726283. Epub 2021 Apr 13.
Delirium is a common occurrence in cardiac and cardiovascular surgical intensive care units. Due to multiple confounding factors, this diagnosis remains challenging for medical professionals. Multiple theories exist regarding the pathophysiology of delirium, which include disruption of neurotransmitters as well as inflammation. Delirium has been associated with prolonged hospitalizations and an increase in mortality. Although there are widely used screening tools for delirium, none have been validated in this particular patient population. Limited treatments exist for delirium, so: both pharmacologic and nonpharmacologic preventative measures should be employed in this patient population.
谵妄是心脏和心血管外科重症监护病房的常见病症。由于多种混杂因素,这一诊断仍然对医疗专业人员具有挑战性。关于谵妄的病理生理学存在多种理论,包括神经递质的破坏以及炎症。谵妄与住院时间延长和死亡率增加有关。尽管有广泛使用的谵妄筛查工具,但没有一种在特定患者群体中得到验证。对于谵妄的治疗方法有限,因此:在这一患者群体中应采用药物和非药物预防措施。