Ocheltree K B, Frizzell L A
Bioacoustics Research Laboratory, University of Illinois, Urbana 61801.
Int J Hyperthermia. 1988 May-Jun;4(3):281-96. doi: 10.3109/02656738809051104.
A technique for calculating the power deposition patterns required to maintain a uniform temperature throughout a tumour by application of the steady-state bioheat transfer equation was reported previously. In this paper the previous analysis is extended to define the power deposition patterns that are required to uniformly raise (and maintain) the temperature throughout the tumour to hyperthermic levels. The power deposition patterns are derived from the time-dependent bioheat transfer equation, and analytical results are developed for infinite half-space and spherical tumour models. A three-dimensional numerical method is presented which allows calculation of time-dependent power deposition patterns for arbitrarily shaped tumours. This method is applied to an example of a spherical tumour.
先前已报道了一种通过应用稳态生物热传递方程来计算使肿瘤内部温度保持均匀所需的功率沉积模式的技术。本文将先前的分析进行扩展，以确定将肿瘤内部温度均匀升高（并维持）至热疗水平所需的功率沉积模式。功率沉积模式由随时间变化的生物热传递方程推导得出，并针对无限半空间和球形肿瘤模型得出了解析结果。本文提出了一种三维数值方法，可用于计算任意形状肿瘤随时间变化的功率沉积模式。该方法应用于一个球形肿瘤实例。
