College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Institute of Clinical Sciences, University of Birmingham, Birmingham, UK.
BMC Health Serv Res. 2021 Apr 14;21(1):345. doi: 10.1186/s12913-021-06329-z.
Tuberculosis is a major global health problem and one of the greatest barriers to its control is poor adherence to treatment. Peru has one of the highest burdens of TB in South America, with an incidence rate of 123 per 100,000 populations. There is currently a lack of evidence in South America about factors that facilitate adherence to treatment, with most previous research focusing on factors that negatively influence adherence to TB treatment.
This study was conducted in Iquitos, the capital city of the Loreto region, north-eastern Peru. Loreto has a high incidence of tuberculosis, estimated at 99 per 100,000 population, and a high poverty rate.
Twenty face-to-face, semi-structured interviews were conducted at two healthcare centres. Data collected from the interviews was analysed using thematic content analysis.
Three main themes emerged from the data set. Personal Qualities, such as responsibility and determination, were perceived as important factors facilitating adherence. Participants described their Trust in Healthcare Providers positively, particularly focusing on their trust in clinical staff, although knowledge of tuberculosis and its treatment was limited. Social Support, from a variety of sources, was also seen as a driving factor for continued adherence.
The results suggest that more emphasis should be placed on educating tuberculosis patients about their disease and its treatment. Additionally, consideration should be given to improving the social support available to patients, for example with tuberculosis support groups involving 'expert' tuberculosis patients.
结核病是全球主要的卫生问题之一,其控制的最大障碍之一是治疗依从性差。秘鲁是南美洲结核病负担最重的国家之一,发病率为每 10 万人中有 123 人。目前南美洲缺乏关于促进治疗依从性的因素的证据,大多数先前的研究都集中在对结核病治疗依从性产生负面影响的因素上。
这项研究在秘鲁东北部洛雷托地区首府伊基托斯进行。洛雷托的结核病发病率很高,估计为每 10 万人中有 99 人,贫困率也很高。
在两个医疗中心进行了 20 次面对面的半结构式访谈。从访谈中收集的数据使用主题内容分析进行分析。
从数据集得出了三个主要主题。个人品质,如责任感和决心,被认为是促进依从性的重要因素。参与者对医疗保健提供者的信任持积极态度,特别是对临床工作人员的信任,尽管他们对结核病及其治疗的了解有限。来自各种来源的社会支持也被视为继续坚持的驱动因素。
研究结果表明,应该更加重视教育结核病患者了解他们的疾病及其治疗方法。此外,应考虑改善为患者提供的社会支持,例如建立结核病支持小组,让“专家”结核病患者参与其中。