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Gabapentin for alcohol use disorder.加巴喷丁用于酒精使用障碍
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Gabapentin reduced drinking in patients with alcohol use disorder and alcohol withdrawal symptoms.加巴喷丁可减少酒精使用障碍和戒断症状患者的饮酒量。
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Gabapentin for the treatment of alcohol use disorder.加巴喷丁用于治疗酒精使用障碍。
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Retrospective analysis of a gabapentin high dose taper compared to lorazepam in acute inpatient alcohol withdrawal.回顾性分析高剂量加巴喷丁逐渐停药与劳拉西泮治疗急性住院酒精戒断的疗效比较。
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Fixed-dose gabapentin augmentation in the treatment of alcohol withdrawal syndrome: a retrospective, open-label study.固定剂量加巴喷丁辅助治疗酒精戒断综合征：一项回顾性、开放性研究。
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A case report of reduction in alcohol craving and protection against alcohol withdrawal by gabapentin.加巴喷丁减轻酒精渴望及预防酒精戒断的病例报告
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The role of gabapentin in the management of alcohol withdrawal and dependence.加巴喷丁在酒精戒断和成瘾管理中的作用。
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Gabapentin dependence and withdrawal requiring an 18-month taper in a patient with alcohol use disorder: a case report.伴有酒精使用障碍的患者出现加巴喷丁依赖和戒断，需要进行 18 个月的逐渐减量：病例报告。
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Novel anticonvulsants in the treatment of alcoholism.新型抗惊厥药在酒精中毒治疗中的应用
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Gabapentin reduces alcohol consumption and craving: a randomized, double-blind, placebo-controlled trial.加巴喷丁可减少酒精摄入量和饮酒欲望：一项随机、双盲、安慰剂对照试验。
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PLoS One. 2024 Feb 26;19(2):e0297948. doi: 10.1371/journal.pone.0297948. eCollection 2024.
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GABAergic signaling in alcohol use disorder and withdrawal: pathological involvement and therapeutic potential.酒精使用障碍和戒断时的 GABA 能信号传递：病理性参与和治疗潜力。
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Medications for the Treatment of Alcohol Dependence-Current State of Knowledge and Future Perspectives from a Public Health Perspective.酒精依赖治疗药物——从公共卫生角度看现有知识和未来展望。
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本文引用的文献

1
Pharmacologic treatment of alcohol use disorder.酒精使用障碍的药物治疗。
Can Fam Physician. 2020 Aug;66(8):583.
2
Trends in gabapentinoid prescribing, co-prescribing of opioids and benzodiazepines, and associated deaths in Scotland.苏格兰加巴喷丁类药物处方、阿片类药物和苯二氮䓬类药物联合处方的趋势及相关死亡情况。
Br J Anaesth. 2020 Aug;125(2):159-167. doi: 10.1016/j.bja.2020.05.017. Epub 2020 Jun 19.
3
Efficacy of Gabapentin for the Treatment of Alcohol Use Disorder in Patients With Alcohol Withdrawal Symptoms: A Randomized Clinical Trial.加巴喷丁治疗伴有酒精戒断症状的酒精使用障碍患者的疗效：一项随机临床试验。
JAMA Intern Med. 2020 May 1;180(5):728-736. doi: 10.1001/jamainternmed.2020.0249.
4
Trends in gabapentin and baclofen exposures reported to U.S. poison centers.美国中毒控制中心报告的加巴喷丁和巴氯芬暴露趋势。
Clin Toxicol (Phila). 2020 Jul;58(7):763-772. doi: 10.1080/15563650.2019.1687902. Epub 2019 Dec 1.
5
A meta-analysis of the efficacy of gabapentin for treating alcohol use disorder.一项关于加巴喷丁治疗酒精使用障碍疗效的荟萃分析。
Addiction. 2019 Sep;114(9):1547-1555. doi: 10.1111/add.14655. Epub 2019 Jun 5.
6
Gabapentin misuse.加巴喷丁滥用。
CMAJ. 2019 Jan 14;191(2):E47. doi: 10.1503/cmaj.180599.
7
Gabapentin, opioids, and the risk of opioid-related death: A population-based nested case-control study.加巴喷丁、阿片类药物与阿片类药物相关死亡风险：一项基于人群的巢式病例对照研究。
PLoS Med. 2017 Oct 3;14(10):e1002396. doi: 10.1371/journal.pmed.1002396. eCollection 2017 Oct.
8
Gabapentin misuse, abuse and diversion: a systematic review.加巴喷丁的误用、滥用及转移：一项系统综述
Addiction. 2016 Jul;111(7):1160-74. doi: 10.1111/add.13324. Epub 2016 Mar 18.
9
Alcohol dosing and total mortality in men and women: an updated meta-analysis of 34 prospective studies.男性和女性的酒精摄入量与总死亡率：对34项前瞻性研究的最新荟萃分析。
Arch Intern Med. 2006;166(22):2437-45. doi: 10.1001/archinte.166.22.2437.

Gabapentin for alcohol use disorder.

作者信息

Weresch Justin, Kirkwood Jessica, Korownyk Christina S

机构信息

Family physician at McMaster Family Practice in Hamilton, Ont.

Family physician at Boyle McCauley Health Centre in Edmonton, Alta.

出版信息

Can Fam Physician. 2021 Apr;67(4):269. doi: 10.46747/cfp.6704269.

DOI:10.46747/cfp.6704269
PMID:33853915
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8324154/
Abstract
摘要