Álvarez Artero E, Campo Núñez A, Garcia Bravo M, García García I, Belhassen Garcia M, Pardo Lledías J
Moncef Belhassen Garcia, Servicio de Medicina Interna. Sección de Enfermedades Infecciosas. CAUSA. IBSAL. CIETUS, Universidad de Salamanca. Paseo San Vicente 58-182, 37007, Salamanca, Spain.
Rev Esp Quimioter. 2021 Jun;34(3):249-253. doi: 10.37201/req/156.2020. Epub 2021 Apr 15.
Urinary tract infections are one of the most common community infections. The diagnosis of urinary infections in the elderly is complex because of its presentation and clinic. The aim of this article is to evaluate the usefulness of blood cultures in febrile urinary tract infection in elderly patients, risk factors, causes of discordance between urine and blood cultures, usefulness of biomarkers and mortality.
Observational study of patients admitted over 65 years old, with urinary infections.
A total of 216 episodes with urinary infections and blood cultures performed. 70 (32,4%) cases with bacteremia. The most frequently detected isolates in blood cultures were: Escherichia coli 50 (71,4%) and Proteus spp. 6 (8,5%). Only septic shock was associated with a higher frequency of bacteraemia (OR=2,93, IC 95: 1,0-8,5; p=0,04). In 26 of the blood cultures a different isolation of the urine culture was detected. Overall mortality was 9.1%, with no association with the presence of bacteremia (p>0. 05).
One third of elderly people hospitalized by tract urinary infection had bacteremia. Their detection was not associated with overall mortality. Disagree between blood and urine cultures in febrile is frequent, especially in patients with recent antibiotic treatment or recently hospitalized.
尿路感染是最常见的社区感染之一。由于其临床表现和临床情况,老年患者尿路感染的诊断较为复杂。本文旨在评估血培养在老年发热性尿路感染中的实用性、危险因素、血培养与尿培养结果不一致的原因、生物标志物的实用性及死亡率。
对65岁以上因尿路感染入院的患者进行观察性研究。
共进行了216次尿路感染发作及血培养。70例(32.4%)发生菌血症。血培养中最常检测到的分离菌为:大肠埃希菌50例(71.4%)和变形杆菌属6例(8.5%)。仅感染性休克与菌血症发生率较高相关(OR=2.93,95%置信区间:1.0 - 8.5;p=0.04)。在26次血培养中检测到与尿培养不同的分离菌。总体死亡率为9.1%,与菌血症的存在无关(p>0.05)。
三分之一因尿路感染住院的老年人发生菌血症。菌血症的检测与总体死亡率无关。发热患者血培养与尿培养结果不一致很常见,尤其是近期接受过抗生素治疗或近期住院的患者。