Department of Cardiology, MD Kars Harakani State Hospital, Kars, Turkey.
Department of Cardiology, MD Kafkas University Medical Faculty, Kars, Turkey.
Biomark Med. 2021 May;15(7):489-495. doi: 10.2217/bmm-2020-0705. Epub 2021 Apr 15.
Monocyte to high-density lipoprotein cholesterol ratio (MHR) has recently emerged as a predictor of cardio-cerebrovascular diseases. Since around one-fifth of strokes are linked to atherosclerosis carotid artery, we aimed to present the relationship between carotid artery disease (CAD) and MHR value in acute ischemic stroke (AIS). A total of 209 adult AIS patients analyzed. Patients divided into two groups in respect to the existence of CAD. MHR was compared between the two groups. MHR with a cut off of 17.23 predicted the presence of disease in the carotid artery, with a sensitivity of 91.9% and specificity of 66.7. MHR was the independent predictor for the presence of disease in the carotid artery. MHR was found to be an independent predictor for the CAD in AIS. Therefore, in AIS patients with high MHR value, CAD should be examined more carefully.
单核细胞/高密度脂蛋白胆固醇比值（MHR）最近被认为是心脑血管疾病的预测因子。由于大约五分之一的中风与颈动脉粥样硬化有关，我们旨在探讨急性缺血性中风（AIS）患者中颈动脉疾病（CAD）与 MHR 值之间的关系。共分析了 209 例成年 AIS 患者。根据 CAD 的存在，将患者分为两组。比较两组间的 MHR。MHR 截断值为 17.23 预测颈动脉疾病的存在，其敏感性为 91.9%，特异性为 66.7。MHR 是颈动脉疾病存在的独立预测因子。MHR 被发现是 AIS 中 CAD 的独立预测因子。因此，在 MHR 值较高的 AIS 患者中，应更仔细地检查 CAD。
