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儿童 COVID-19 相关多系统炎症综合征所致双侧急性前葡萄膜炎和角膜点状上皮病变。

Bilateral Acute Anterior Uveitis and Corneal Punctate Epitheliopathy in Children Diagnosed with Multisystem Inflammatory Syndrome Secondary to COVID-19.

机构信息

Department of Ophthalmology, Health Sciences University, Dr. Sami Ulus Education and Research Hospital, Ankara, Turkey.

Department of Pediatric Infectious Diseases, Health Sciences University, Dr. Sami Ulus Education and Research Hospital, Ankara, Turkey.

出版信息

Ocul Immunol Inflamm. 2021 May 19;29(4):700-704. doi: 10.1080/09273948.2021.1909070. Epub 2021 Apr 15.

DOI:10.1080/09273948.2021.1909070
PMID:33856952
Abstract

: To report bilateral anterior uveitis and corneal punctate epitheliopathy in children with multisystem inflammatory syndrome (MIS-C) secondary to coronavirus disease (COVID-19).: Five patients who were positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies and diagnosed with MIS-C were evaluated. Ophthalmologic examinations were performed in order to reveal ocular findings in MIS-C disease.: Slit lamp examinations showed bilateral non-granulomatous acute anterior uveitis in all patients and severe corneal punctuate epitheliopathy in three of the patients. These ocular findings mostly disappeared with treatment in about one week.: Bilateral non-granulomatous acute anterior uveitis and dry eye can be detected in patients diagnosed with MIS-C secondary to COVID-19. Even if generally, COVID-19 is not a life threatening disease in children by itself, inflammatory ocular manifestations can be detected in MIS-C secondary to COVID-19.

摘要

报告 5 例儿童多系统炎症综合征(MIS-C)继发于冠状病毒病(COVID-19)的双侧前葡萄膜炎和角膜点状上皮病:对 5 例 SARS-CoV-2 抗体阳性并诊断为 MIS-C 的患者进行评估。为了揭示 MIS-C 疾病的眼部表现,进行了眼科检查:裂隙灯检查显示所有患者均有双侧非肉芽肿性急性前葡萄膜炎,3 例患者有严重的角膜点状上皮病。这些眼部表现在用大约一周的时间治疗后大多消失:在诊断为 COVID-19 继发的 MIS-C 的患者中可以检测到双侧非肉芽肿性急性前葡萄膜炎和干眼症。即使 COVID-19 本身在儿童中不是一种危及生命的疾病,但在 COVID-19 继发的 MIS-C 中也可以检测到炎症性眼部表现。

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