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儿童 SARS-CoV-2 相关多系统炎症综合征中双侧前葡萄膜炎和中葡萄膜炎。

Bilateral anterior and intermediate uveitis in SARS-CoV-2 associated multisystem inflammatory syndrome in a pediatric patient.

机构信息

Francis I. Proctor Foundation, Department of Ophthalmology, University of California San Francisco, 490 Illinois Street, CA, 94158, San Francisco, USA.

Department of Ophthalmology, University of Colorado School of Medicine, 1675 North Aurora Court F731, CO, 80045, Aurora, USA.

出版信息

Pediatr Rheumatol Online J. 2022 Jul 30;20(1):59. doi: 10.1186/s12969-022-00712-8.

Abstract

PURPOSE

To report a case of bilateral anterior intermediate uveitis after recovery from SARS-CoV-2 associated multisystem inflammatory syndrome in children (MIS-C).

CASE REPORT

A 9-year-old male presented with bilateral anterior intermediate uveitis with fluorescein angiography (FA) leakage of the disc and peripheral vasculature 1 month after recovery from MIS-C. He was treated with difluprednate 0.05% in both eyes with resolution of FA leakage, but our patient has required an extended treatment of topical therapy and the need long term immunosuppression.

CONCLUSIONS

This is a case of uveitis presenting after recent MIS-C related to SARS-CoV-2. Ongoing follow up and monitoring is required, and it is important for the ophthalmologist and rheumatologist to be aware of this rare complication during the current COVID-19 pandemic.

摘要

目的

报告 1 例儿童严重急性呼吸综合征冠状病毒 2 相关多系统炎症综合征(MIS-C)康复后出现双侧前部中等级别葡萄膜炎。

病例报告

1 例 9 岁男性,MIS-C 康复后 1 个月出现双侧前部中等级别葡萄膜炎,伴视盘和周边血管荧光素血管造影(FA)渗漏。他接受了双眼双氯芬酸钠 0.05%治疗,FA 渗漏得到缓解,但我们的患者需要延长局部治疗和长期免疫抑制治疗。

结论

这是一例最近与 SARS-CoV-2 相关的 MIS-C 后出现的葡萄膜炎。需要进行持续的随访和监测,在当前 COVID-19 大流行期间,眼科医生和风湿病医生需要意识到这种罕见的并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbb9/9338464/c141bb0a2ec9/12969_2022_712_Fig1_HTML.jpg

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