University of Mostar Clinical Hospital, Department of Gastroenterology and Hepatology, Bijeli Brijeg bb, 88000 Mostar, Bosnia and Herzegovina,
Psychiatr Danub. 2021 Spring;33(1):48-56. doi: 10.24869/psyd.2021.48.
To explore corellation of anxiety, depression ant type of personality in inflammatory bowel disease (IBD) and compare with peptic ulcer (PU).
In this study, prevalence of anxiety, depression and type of personality was investigated in 362 cases divided into three groups: 112 of IBD patients, 122 of peptic ulcer patients and 128 of control group who didn't have any gastrointestinal or psychic complaints. IBD and peptic ulcer diagnosis were established by standard diagnostic procedures (anamnesis, clinical manifestations, laboratory, endoscopy and biopsy in IBD and upper endoscopy in peptic ulcer). Anxiety and depression were established by Hamilton anxiety rating scale (HAM-A) and Hamilton rating test for depression (HAM-D). Type of A/B personality was established by Bortner scale and D type of personality by Denollet scale (DS14).
Anxiety was found in 47 (41.9%) and depression in 44 (38.3%) of a total of 112 IBD cases. In group with peptic ulcer anxiety was found in 40 (32.8%) and depression aalso in 40 (32.8%) of total 122 cases. In control group anxiety was diagnosed in 21 (16.4%) and depression in 20 (15.6%) of total 128 cases. Anxiety and depresson were significantly higher in both groups than in control group but anxiety and depression were significantly higher in IBD group than peptic ulcer group. D type of personality was statistically significant in peptic ulcer group.
Anxiety and depression in IBD and peptic ulcer cases have a greater prevalence compared to the normal population and surprisingly are higher in IBD than peptic ulcer group. D type of personality is associated with peptic ulcer.
探讨炎症性肠病（IBD）患者焦虑、抑郁与人格类型的相关性，并与消化性溃疡（PU）进行比较。
本研究对 362 例患者进行了研究，分为三组：IBD 患者 112 例，消化性溃疡患者 122 例，无胃肠道或精神症状的对照组 128 例。IBD 和消化性溃疡的诊断依据为标准诊断程序（病史、临床表现、实验室、内镜和活检用于 IBD，上消化道内镜用于消化性溃疡）。采用汉密尔顿焦虑量表（HAM-A）和汉密尔顿抑郁量表（HAM-D）评定焦虑和抑郁。采用 Bortner 量表评定 A/B 型人格，采用 Denollet 量表（DS14）评定 D 型人格。
IBD 组 112 例患者中，47 例（41.9%）存在焦虑，44 例（38.3%）存在抑郁；消化性溃疡组 122 例患者中，40 例（32.8%）存在焦虑，40 例（32.8%）存在抑郁；对照组 128 例患者中，21 例（16.4%）存在焦虑，20 例（15.6%）存在抑郁。两组的焦虑和抑郁发生率均明显高于对照组，但 IBD 组的焦虑和抑郁发生率明显高于消化性溃疡组。消化性溃疡组 D 型人格统计学显著。
IBD 和消化性溃疡患者的焦虑和抑郁发生率高于普通人群，且令人惊讶的是，IBD 患者的发生率高于消化性溃疡患者。D 型人格与消化性溃疡相关。
