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特布他林定量吸入剂与异丙喘宁手持式雾化吸入对比:针对城市中心区黑人慢性阻塞性肺疾病患者的比较

Terbutaline metered-dose inhalation vs metaproterenol by hand-held nebulization: a comparison in black inner-city COPD patients.

作者信息

Greene A B, Jackson C L

出版信息

J Natl Med Assoc. 1988 Apr;80(4):393-6.

PMID:3385785
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2625758/
Abstract

A greater percentage of the inner-city black population suffers from chronic obstructive pulmonary disease (COPD) than does the white population in general. Urban black patients are also more likely than urban white patients to receive primary care for their COPD symptoms in area emergency rooms, which can affect the resources available for medical care in these institutions. The present study compared the standard of therapy at Provident Medical Center, metaproterenol, administered by a hand-held nebulizer (HHN), with therapy using terbutaline, administered by a metered-dose inhaler (MDI) with a spacer, in 60 black patients with mild to moderate respiratory distress.Measurements of peak expiratory flow rates before and after therapy indicated that both methods of treatment provided similar relief. The terbutaline MDI modality, however, required less equipment and therapist time, and patients could continue the same therapy at home. All 60 patients were sent home on terbutaline MDI therapy. Follow-up by questionnaire, two to three weeks later, showed 95 percent of 36 respondents preferred the terbutaline MDI with spacer compared with their previous therapy.

摘要

与普通白人相比,城市中心黑人患慢性阻塞性肺疾病(COPD)的比例更高。城市黑人患者在地区急诊室因COPD症状接受初级护理的可能性也比城市白人患者更高,这可能会影响这些机构可用于医疗护理的资源。本研究比较了普罗维登斯医疗中心对60名患有轻度至中度呼吸窘迫的黑人患者使用手持雾化器(HHN)给予间羟异丙肾上腺素的治疗标准与使用带储雾罐的定量吸入器(MDI)给予特布他林的治疗效果。治疗前后的呼气峰值流速测量表明,两种治疗方法提供的缓解效果相似。然而,特布他林MDI治疗方式所需设备和治疗师时间更少,患者在家中也可以继续相同的治疗。所有60名患者均接受特布他林MDI治疗后出院。两到三周后通过问卷调查进行随访,结果显示,在36名受访者中,95%的人表示与之前的治疗相比,他们更喜欢带储雾罐的特布他林MDI。

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Prevalence of asthma and health service utilization of asthmatic children in an inner city.内城区哮喘儿童的哮喘患病率及医疗服务利用情况
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