Department of Physical Medicine and Rehabilitation, Oslo University Hospital, Oslo, Norway.
Institute of Health and Society, Research Centre for Habilitation and Rehabilitation Models & Services (CHARM), Faculty of Medicine, University of Oslo, Oslo, Norway.
Clin Rehabil. 2021 Oct;35(10):1428-1441. doi: 10.1177/02692155211010369. Epub 2021 Apr 15.
To determine the effectiveness of a family-centred intervention for patients with traumatic brain injury and family members.
Open-labelled, two-armed randomised controlled trial.
Outpatient clinic and family residences.
Sixty-one patients (33 women) with traumatic brain injury, with mean (SD) age 43.8 (12.2), and 63 family members (33 women), with mean (SD) age 42.6 (11.3), were assign to intervention ( = 30 families) and control group ( = 31 families).
An eight-session single-family intervention to improve individual and family functioning.
Self-reported questionnaires at start-of-treatment, median (IQR) 11.4 (8.4, 15.9) months post-injury, and at two follow-ups, 2.7 (2.3, 3.8) and 9.2 (8.2, 9.9) months after start-of-treatment. Primary outcome measures were the SF-36 Mental Component Summary (MCS) and Caregiver Burden Scale (CGB). Secondary outcome measures were the Family Adaptability and Cohesion Evaluation Scale (FACES) and Quality of Life after Brain Injury Questionnaire (QOLIBRI). Group differences were analysed with linear mixed-model analysis for repeated measurements.
No significant between-group differences were found. The intervention group significantly improved on the MCS, the CGB and FACES in the treatment period, whereas the controls did not. The mean (SD) MCS change in the treatment period was 2.4 (1.1) points = 0.028 in the intervention group. Mean (SE) MCS scores were 47.9 (1.26) and 47.3 (1.27) in the intervention and control group at last follow-up.
Receiving an eight-session family intervention, in addition to specialised rehabilitation for the patients, was not superior to rehabilitation at a specialised traumatic brain injury outpatient clinic.
评估针对创伤性脑损伤患者及其家属的以家庭为中心的干预措施的有效性。
开放性、双臂随机对照试验。
门诊诊所和家庭住所。
61 名创伤性脑损伤患者（33 名女性），平均（SD）年龄 43.8（12.2）岁，63 名家庭成员（33 名女性），平均（SD）年龄 42.6（11.3）岁，分为干预组（=30 个家庭）和对照组（=31 个家庭）。
八节单次家庭干预，以改善个体和家庭功能。
治疗开始时、受伤后中位数（IQR）11.4（8.4，15.9）个月以及治疗开始后两个随访时间（2.7（2.3，3.8）和 9.2（8.2，9.9）个月）时的自我报告问卷。主要结局测量指标是 SF-36 心理健康成分量表（MCS）和照顾者负担量表（CGB）。次要结局测量指标是家庭适应性和凝聚力评估量表（FACES）和脑损伤后生活质量问卷（QOLIBRI）。采用重复测量线性混合模型分析进行组间差异分析。
未发现组间差异。干预组在治疗期间 MCS、CGB 和 FACES 显著改善，而对照组没有。治疗期间 MCS 的平均（SD）变化为 2.4（1.1）分，差异有统计学意义（=0.028）。干预组最后随访时的平均（SE）MCS 评分为 47.9（1.26），对照组为 47.3（1.27）。
除了为患者提供专门的康复治疗外，接受八节家庭干预措施并不优于专门的创伤性脑损伤门诊康复治疗。
