Gatland D J, Youngs R P, Jeffrey I J
E.N.T. Department, St. Bartholomews Hospital, London, England.
J Otolaryngol. 1988 Apr;17(2):131-3.
A case of cholesterol granuloma of the maxillary antrum is presented, the eighth reported case in the ENT literature. It is postulated that a maxillary antral cholesterol granuloma could be associated with obstruction of the antral ostia, hemorrhage into polypoidal mucosal disease or that an antral cyst may have developed a cholesterol granuloma in its walls as a result of cholesterol precipitation. A review of the literature on cholesterol granuloma suggests that it is a condition which arises in a closed space with poor ventilation or drainage, with long-standing inflammation with effusion or hemorrhage contributing to the formation of free cholesterol crystals derived from tissue or blood breakdown products. The foreign body granuloma produced in this way is then self-perpetuating and requires complete removal for cure rather than a simple drainage procedure.
本文报告一例上颌窦胆固醇肉芽肿病例，这是耳鼻喉科文献中报道的第八例。据推测，上颌窦胆固醇肉芽肿可能与窦口阻塞、息肉样黏膜病变出血有关，或者是窦囊肿壁因胆固醇沉淀而形成了胆固醇肉芽肿。对胆固醇肉芽肿文献的回顾表明，这种病症发生在通风或引流不良的封闭空间内，长期的炎症伴渗出或出血促使源自组织或血液分解产物的游离胆固醇晶体形成。以这种方式产生的异物肉芽肿会自行持续存在，需要彻底切除才能治愈，而不是简单的引流手术。
